Histone Methylation

  • (R)-PFI-2 HCl | Methyltransferase SETD7 inhibitor

    CAS:
    1627607-87-7
    Catalog Number:
    10-4033
    Activity:
    Methyltransferase SETD7 inhibitor
    Chemical Name:
    (1R)-1-[[3-(Trifluoromethyl)phenyl]methyl]-2-oxo-2-(1-pyrrolidinyl)ethyl-1,2,3,4-tetrahydro-6-isoquinolinesulfonamide hydrochloride
    Molecular Weight:
    535.98
    Molecular Formula:
    C23H25F4N3O3S HCl
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $75.00
  • A-196 | SUV420H1/H2 methyltransferase inhibitor

    CAS:
    1982372-88-2
    Catalog Number:
    10-4018
    Activity:
    SUV420H1/H2 methyltransferase inhibitor
    Chemical Name:
    Cyclopentyl-(6,7-dichloro-4-pyridin-4-yl-phthalazin-1-yl)-amine
    Molecular Weight:
    359.25
    Molecular Formula:
    C18H16Cl2N4
    Solubility:
    Soluble in DMSO (up to 5 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $70.00
  • BIX-01294 | Histone Methyltransferase inhibitor

    CAS:
    935693-62-2
    Catalog Number:
    10-1335
    Activity:
    Histone Methyl transferase inhibitor
    Chemical Name:
    2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine trihydrochloride
    Molecular Weight:
    600.02
    Molecular Formula:
    C28H38N6O2
    Solubility:
    Soluble in DMSO (up to 50 mg/ml), or in Water (up to 50 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    >98% by TLC
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $60.00
  • Chaetocin | Lys methyltransferase inhibitor

    CAS:
    28097-03-2
    Catalog Number:
    10-2404
    Activity:
    Lys methyltransferase inhibitor
    Chemical Name:
    Isolated from Chaetomium species
    Molecular Weight:
    696.85
    Molecular Formula:
    C30H28N6O6S4
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98%
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $50.00
  • DZNep HCl | Methyltransferase inhibitor

    CAS:
    120964-45-6
    Catalog Number:
    10-1524
    Activity:
    Methyl transferase inhibitor
    Chemical Name:
    (1S,2R,5R)-5-(4-Aminoimidazo[4,5-c]pyridine-1-yl)-3-(hydroxymethyl)-cyclopent-3-ene-1,2-diol hydrochloride
    Alternate Names:
    3-Deazaneplanocin A HCl; NSC 617989
    Molecular Weight:
    298.73
    Molecular Formula:
    C12H14N4O3 ·HCl
    Solubility:
    Soluble in Water (up to 40 mg/ml)
    Physical Properties:
    Beige solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $142.00
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