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Smoothened

  • 20(S)-Hydroxycholesterol | Smoothened activator

    CAS:
    516-72-3
    Catalog Number:
    10-4540
    Activity:
    Smoothened activator
    Chemical Name:
    5-Cholesten-3β, 20α-diol
    Molecular Weight:
    402.66
    Molecular Formula:
    C27H46O2
    Solubility:
    Soluble in DMSO or in Ethanol.
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • CUR 61414 | Hedgehog pathway antagonist

    CAS:
    334998-36-6
    Catalog Number:
    10-1392
    Activity:
    Hedgehog pathway antagonist
    Chemical Name:
    N-[(3S,5S)-1-(1,3-Benzodioxol-5-ylmethyl)-5-(1-piperazinylcarbonyl)-3-pyrrolidinyl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide
    Molecular Weight:
    550.71
    Molecular Formula:
    C31H42N4O5
    Solubility:
    Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    Tan solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $90.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Cyclopamine | Inhibits hedgehog signaling

    CAS:
    4449-51-8
    Catalog Number:
    10-1082
    Activity:
    Inhibits hedgehog signaling
    Molecular Weight:
    411.63
    Molecular Formula:
    C27H41NO2
    Solubility:
    Soluble in DMSO (up to 4 mg/ml) or in Ethanol (up to 20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $56.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Jervine | Hedgehog pathway inhibitor

    CAS:
    469-59-0
    Catalog Number:
    10-2388
    Activity:
    Hedgehog pathway
    Alternate Names:
    11-Ketocyclopamine
    Chemical Name:
    (3β,23β)-17,23-Epoxy-3-hydroxyveratraman-11-one
    Molecular Weight:
    425.62
    Molecular Formula:
    C27H39NO3
    Solubility:
    Soluble in DMSO (up to 5 mg/ml), in DMF (up to 6 mg/ml), or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO, ethanol or DMF may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $85.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Purmorphamine | Smoothened activator

    CAS:
    483367-10-8
    Catalog Number:
    10-4622
    Activity:
    Smoothened activator
    Chemical Name:
    1-(1-Naphthoxy)-6-(4-morpholinoanilino)-9-cyclohexylpurine
    Molecular Weight:
    520.62
    Molecular Formula:
    C31H32N6O2
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $75.00
    View Product This product has multiple variants. The options may be chosen on the product page
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