Smoothened

  • SAG | Smoothened agonist

    CAS:
    912545-86-9 (free base)
    Catalog Number:
    10-4525
    Activity:
    Smoothened agonist
    Alternate Names:
    Smoothened Agonist
    Chemical Name:
    3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thiiophene-2-carboxamide dihydrochloride
    Molecular Weight:
    562.98
    Molecular Formula:
    C28H28ClN3OS 2HCl
    Solubility:
    Soluble in DMSO (up to 20 mg/ml), in DMF (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    Solid
    Storage Temperature:
    -20°
    Shipping Code:
    RT
    From $35.00
  • Vismodegib | Sonic Hedgehog signaling pathway inhibitor

    CAS:
    879085-55-9
    Catalog Number:
    10-2182
    Activity:
    Sonic Hedgehog signaling pathway inhibitor
    Chemical Name:
    2-Chloro-N-(4-chloro-3-(pyridine-2-yl)phenyl)-4-(methylsulfonyl)benzamide
    Alternate Names:
    GDC-0449
    Molecular Weight:
    421.3
    Molecular Formula:
    C19H14Cl2N2O3S
    Solubility:
    Soluble in DMSO (up to 200 mg/ml) or in Ethanol (up to 10 mg/ml with warming)
    Physical Properties:
    Off-white or beige solid
    Purity:
    99% by TLC and HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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