RAF

  • Dabrafenib | B-Raf mutant inhibitor

    CAS:
    1195765-45-7
    Catalog Number:
    10-1569
    Activity:
    B-Raf mutant inhibitor
    Chemical Name:
    N-[3-[5-(2-amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluoro-benzenesulfonamide
    Alternate Names:
    GSK2118436
    Molecular Weight:
    519.56
    Molecular Formula:
    C23H20F3N5O2S
    Solubility:
    Soluble in DMSO (up to 30 mg/ml with warming), or in Ethanol (up to 1 mg/ml with warming).
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • GW-5074 | c-Raf1 inhibitor

    CAS:
    220904-83-6
    Catalog Number:
    10-1031
    Activity:
    c-Raf1 inhibitor
    Chemical Name:
    3-(3,5-Dibromo-4-hydroxybenzylidene)-5-iodo-1,3-dihydroindol-2-one
    Molecular Weight:
    520.95
    Molecular Formula:
    C15H8Br2INO2
    Solubility:
    Soluble in DMSO (up to 50 mg/ml).
    Physical Properties:
    Dark orange solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Locostatin | RKIP/Raf-1 kinase disruptor

    CAS:
    133812-16-5
    Catalog Number:
    10-5381
    Activity:
    RKIP/Raf-1 kinase disruptor
    Chemical Names:
    (4S)-3-[(E)-But-2-enoyl]-4-benzyl-2-oxazolidinone; UIC-1005
    Molecular Weight:
    245.28
    Molecular Formula:
    C14H15O3
    Solubility:
    Soluble in DMSO (60 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $48.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • PLX4032 | BRAF inhibitor

    CAS:
    918504-65-1
    Catalog Number:
    10-2928
    Activity:
    BRAF inhibitor
    Chemical Name:
    N-[3-[[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide
    Alternate Names:
    Vemurafenib, R7204, Ro 51-85426
    Molecular Weight:
    489.92
    Molecular Formula:
    C23H18ClF2N3O3S
    Solubility:
    Soluble in DMSO (up to 100 mg/ml)
    Physical Properties:
    White or off-white solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • PLX4720 | Mutant B-Raf inhibitor

    CAS:
    918505-84-7
    Catalog Number:
    10-5113
    Activity:
    Mutant B-Raf inhibitor
    Chemical Names:
    N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide
    Molecular Weight:
    413.82
    Molecular Formula:
    C17H14ClF2N3O3S
    Solubility:
    Soluble in DMSO (30 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $55.00
    View Product This product has multiple variants. The options may be chosen on the product page
1 2

20% OFF

For Postdoc
Customers!