Growth Factor

  • ABT-869 | Dual VEGFR and PDGFR kinase inhibitor

    ABT-869 (796967-16-3) ia a structurally novel, potent inhibitor of receptor tyrosine kinases inhibiting VEGFR and PDGFR and related kinases with IC50s= 3, 4, 4, 66, 3 […]

    From $55.00
  • Afatinib | EGFR and HER2 inhibitor

    CAS:
    850140-72-6
    Catalog Number:
    10-4510
    Activity:
    EGFR and HER2 inhibitor
    Chemical Name:
    N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4(dimethylamino)-2E-butenamide
    Alternate Names:
    BIBW2992
    Molecular Weight:
    485.94
    Molecular Formula:
    C24H25ClFN5O3
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    Pale yellow solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $45.00
  • AG 1478 | EGFR kinase inhibitor

    CAS:
    175178-82-2
    Catalog Number:
    10-2117
    Activity:
    EGFR kinase inhibitor
    Chemical Name:
    N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinanine, free base
    Molecular Weight:
    315.76
    Molecular Formula:
    C16H14ClN3O2
    Solubility:
    Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 10 mg/ml with warming).
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $50.00
  • AG-1296 | PDGFR kinase inhibitor

    CAS:
    146535-11-7
    Catalog Number:
    10-1087
    Activity:
    PDGFR kinase inhibitor
    Chemical Name:
    6,7-Dimethoxy-3-phenylquinoxaline
    Molecular Weight:
    266.3
    Molecular Formula:
    C16H14N2O2
    Solubility:
    Soluble in DMSO.
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
  • AG-1517 HCl | EGFR kinase inhibitor

    CAS:
    153436-54-5
    Catalog Number:
    10-1377
    Activity:
    EGFR kinase inhibitor
    Alternate Names:
    PD153,053; SU-5271; Z-252868
    Chemical Name:
    4-(3-Bromoanilino)-6,7-dimethoxyquinazoline hydrochloride
    Molecular Weight:
    360.21
    Molecular Formula:
    C16H14BrN3O2
    Solubility:
    Soluble in DMSO (up to 5 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $70.00
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