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Epigenetic TME Modulation

  • 5-azacytidine chemical structure

    5-Azacytidine | DNA hypomethylation agent

    CAS:
    320-67-2
    Catalog Number:
    10-1267
    Activity:
    DNA hypomethylation agent
    Alternate Names:
    Ladakamycin; U-18496; NSC-102816; AzaC
    Chemical Name:
    4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
    Molecular Weight:
    244.21
    Molecular Formula:
    C8H12N4O5
    Solubility:
    Soluble in DMSO (up to 25 mg/ml), or in Water (up to 12 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $20.00
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  • Decitabine | DNA hypomethylation agent

    CAS:
    2353-33-5
    Catalog Number:
    10-2412
    Activity:
    DNA hypomethylation agent
    Alternate Names:
    NSC-127716
    Chemical Name:
    5-Aza-2′-deoxycytidine
    Molecular Weight:
    228.21
    Molecular Formula:
    C8H12N4O4
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Water (up to 11 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • GSK2879552 | Potent and selective LSD1 inhibitor

    CAS:
    1401966-69-5
    Catalog Number:
    10-4020
    Activity:
    Potent and selective LSD1 inhibitor
    Chemical Name:
    4-[[4-[[[(1R,2S)-2-Phenylcyclopropyl]amino]methyl]-1-piperidinyl]methyl]benzoic acid dihydrochloride
    Molecular Weight:
    437.40
    Molecular Formula:
    C23H28N2O2 • HCl
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Water (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $80.00
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  • I-BET762 | BET Bromodomain inhibitor / Suppresses Myc transcription

    CAS:
    1260907-17-2
    Catalog Number:
    10-4122
    Activity:
    BET Bromodomain inhibitor / Supresses Myc transcription
    Chemical Name:
    (4S)- 6-(4-Chlorophenyl)-N-ethyl-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetamide
    Alternate Names:
    GSK525762
    Molecular Weight:
    423.90
    Molecular Formula:
    C22H22ClN5O2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to at least 25 mg/ml)
    Physical Properties:
    Tan solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $80.00
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  • MS-275 (Entinostat) | HDAC inhibitor

    CAS:
    209783-80-2
    Catalog Number:
    10-2131
    Activity:
    HDAC inhibitor
    Alternate Names:
    Entinostat; SNDX-275
    Molecular Weight:
    376.42
    Molecular Formula:
    C21H20N4O3
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
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