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Epigenetic TME Modulation

  • Panobinostat | HDAC inhibitor

    CAS:
    404950-80-7
    Catalog Number:
    10-2157
    Activity:
    HDAC inhibitor
    Alternate Names:
    LBH-589
    Chemical Name:
    (E)-N-Hydroxy-3-(4-((2-(2-methyl-1H-indol-3-yl)ethylamino)methyl)phenyl)acrylamide
    Molecular Weight:
    349.44
    Molecular Formula:
    C21H23N3O2
    Solubility:
    Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • SAHA | HDAC inhibitor

    CAS:
    149647-78-9
    Catalog Number:
    10-1067
    Activity:
    HDAC inhibitor
    Alternate Names:
    Vorinostat
    Chemical Name:
    Suberoylanilide-hydroxamic acid
    Molecular Weight:
    264.33
    Molecular Formula:
    C14H20N2O3
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 2 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 6 months.
    Shipping Code:
    RT
    From $35.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Tazemetostat | EZH2 inhibitor

    CAS:
    1403254-99-8
    Catalog Number:
    10-4032
    Activity:
    EZH2 inhibitor
    Chemical Name:
    N-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4’-(morpholinomethyl)-[1,1’-biphenyl]-3-carboxamide
    Alternate Name:
    EPZ-6438
    Molecular Weight:
    572.75
    Molecular Formula:
    C34H44N4O4
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $55.00
    View Product This product has multiple variants. The options may be chosen on the product page
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