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Tryptophan Metabolism

  • Epacadostat | IDO1 inhibitor

    CAS:
    1204669-58-8
    Catalog Number:
    10-4499
    Activity:
    IDO1 inhibitor/ Cancer immunotherapy enhancer
    Chemical Name:
    N-(3-Bromo-4-fluorophenyl)-N’-hydroxy-4-{[2-(sulfamoylamino)ethyl]amino}-1,2,5-oxadiazole-3-carboximidamide
    Alternate Name:
    INCB024360
    Molecular Weight:
    438.23
    Molecular Formula:
    C11H13BrFN7O4S
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $45.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Indoximod | IDO modulator / tryptophan mimetic

    CAS:
    110117-83-4
    Catalog Number:
    10-4569
    Activity:
    IDO modulator / tryptophan mimetic
    Chemical Name:
    1-Methyl-D-tryptophan
    Molecular Weight:
    218.25
    Molecular Formula:
    C12H14N2O2
    Solubility:
    Soluble in DMSO (greater than 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    >98%
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $35.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Linrodostat | IDO1 inhibitor

    CAS:
    1923833-60-6
    Catalog Number:
    10-4473
    View Product This product has multiple variants. The options may be chosen on the product page

  • NLG919 | IDO pathway inhibitor

    CAS:
    1402836-58-1
    Catalog Number:
    10-4564
    Activity:
    IDO pathway inhibitor
    Chemical Names:
    1-Cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol
    Molecular Weight:
    282.39
    Molecular Formula:
    C18H22N2O
    Solubility:
    Soluble in DMSO (up to 15 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • PF-06840003 | IDO1 inhibitor

    CAS:
    198474-05-4
    Catalog Number:
    10-4498
    Activity:
    IDO1 inhibitor/Cancer immunotherapy enhancer
    Chemical Name:
    3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione
    Alternate Name:
    EOS200271
    Molecular Weight:
    232.21
    Molecular Formula:
    C12H9FN2O2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page