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Chemotherapeutics

  • TH1760 | NUDT15 inhibitor

    CAS:
    2567914-01-4
    Catalog Number:
    10-4624
    Activity:
    NUDT15 inhibitor
    Chemical Names:
    6-[4-(1H-Indole-5-carbonyl)piperazin-1-yl]sulfonyl-3H-1,3-benzoxazol-2-one
    Molecular Weight:
    426.45
    Molecular Formula:
    C20H18N4O5S
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Thalidomide | E3 UB ligase inhibitor

    CAS:
    50-35-1
    Catalog Number:
    10-1115
    Activity:
    E3 UB ligase inhibitor
    Chemical Name:
    N-(2,6-Dioxo-3-piperidinyl)phthalimide, racemic
    Molecular Weight:
    258.25
    Molecular Formula:
    C13H10N2O4
    Solubility:
    Soluble in DMSO (up to 5 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Topotecan HCl | DNA topoisomerase I inhibitor

    CAS:
    119413-54-6
    Catalog Number:
    10-2479
    View Product This product has multiple variants. The options may be chosen on the product page

  • Trametinib | MEK inhibitor

    CAS:
    871700-17-3
    Catalog Number:
    10-4759
    Activity:
    MEK inhibitor
    Chemical Name:
    N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodophenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide
    Alternate Names:
    GSK1120212
    Molecular Weight:
    615.39
    Molecular Formula:
    C26H23FIN5O4
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Trifluorothymidine | Proapoptotic antiproliferative agent

    CAS:
    70-00-8
    Catalog Number:
    10-1283
    Activity:
    Thymidylate synthase inhibitor / Anti-cancer agent
    Chemical Name:
    2’-Deoxy-5-trifluoromethyluridine
    Alternate Names:
    α,α,α-Trifluorothymidine; Trifluorothymine deoxyriboside; Trifluridine; TFT
    Molecular Weight:
    296.20
    Molecular Formula:
    C10H11F3N2O5
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Water (up to 14 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $45.00
    View Product This product has multiple variants. The options may be chosen on the product page
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