Epigenetics Archives

EPZ015666 | Potent and selective PRMT5 inhibitor

CAS:

1616391-65-1

Catalog Number:

10-4031

Activity:

Potent and selective PRMT5 inhibitor

Chemical Name:

(S)-N-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide

Molecular Weight:

383.44

Molecular Formula:

C₂₀H₂₅N₅O₃

Solubility:

Soluble in DMSO (up to 20 mg/ml)

Physical Properties:

White solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $90.00
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Garcinol | HAT inhibitor

CAS:

78824-30-3

Catalog Number:

10-1337

Activity:

HAT inhibitor

Molecular Weight:

602.8

Molecular Formula:

C₃₈H₅₀O₆

Solubility:

Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).

Physical Properties:

Yellow solid

Purity:

>95%

Storage Temperature:

-20°

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. Garcinol is prone to oxidation. Protect from exposure to air.

Shipping Code:

RT

From $70.00
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GSK126 | EZH2 methyltransferase inhibitor

CAS:

1346574-57-9

Catalog Number:

10-3394

Activity:

EZH2 methyltransferase inhibitor

Chemical Names:

N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-methyl-1-[(1S)-1-methylpropyl]-6-[6-(1-piperazinyl)-3-pyridinyl]-1H-indole-4-carboxamide

Molecular Weight:

526.69

Molecular Formula:

C₃₁H₃₈N₆O₂

Solubility:

Soluble in DMSO (16 mg/ml)

Physical Properties:

Cream solid

Purity:

>98% HPLC/TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $70.00
View Product This product has multiple variants. The options may be chosen on the product page
GSK2879552 | Potent and selective LSD1 inhibitor

CAS:

1401966-69-5

Catalog Number:

10-4020

Activity:

Potent and selective LSD1 inhibitor

Chemical Name:

4-[[4-[[[(1R,2S)-2-Phenylcyclopropyl]amino]methyl]-1-piperidinyl]methyl]benzoic acid dihydrochloride

Molecular Weight:

437.40

Molecular Formula:

C₂₃H₂₈N₂O₂ • HCl

Solubility:

Soluble in DMSO (up to 25 mg/ml) or in Water (up to at least 25 mg/ml)

Physical Properties:

White solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $80.00
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GSK3326595 | Selective PRMT5 inhibitor

CAS:

1616392-22-3

Catalog Number:

10-4028

Activity:

Selective PRMT5 inhibitor

Chemical Name:

6-[(1-Acetylpiperidine-4-yl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyrimidine-4-carboxamide

Alternate Name:

EPZ015938

Molecular Weight:

452.56

Molecular Formula:

C₂₄H₃₂N₆O₃

Solubility:

Soluble in DMSO (up to 20 mg/ml).

Physical Properties:

Off-white solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

Shipping Code:

RT

From $50.00
View Product This product has multiple variants. The options may be chosen on the product page

Epigenetics

EPZ015666 | Potent and selective PRMT5 inhibitor

Garcinol | HAT inhibitor

GSK126 | EZH2 methyltransferase inhibitor

GSK2879552 | Potent and selective LSD1 inhibitor

GSK3326595 | Selective PRMT5 inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Epigenetics

EPZ015666 | Potent and selective PRMT5 inhibitor

Garcinol | HAT inhibitor

GSK126 | EZH2 methyltransferase inhibitor

GSK2879552 | Potent and selective LSD1 inhibitor

GSK3326595 | Selective PRMT5 inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21