Epigenetics
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EPZ015666 | Potent and selective PRMT5 inhibitor
From $90.00CAS:1616391-65-1Catalog Number:10-4031Activity:Potent and selective PRMT5 inhibitorChemical Name:(S)-N-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-(oxetan-3-ylamino)pyrimidine-4-carboxamideMolecular Weight:383.44Molecular Formula:C20H25N5O3Solubility:Soluble in DMSO (up to 20 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Garcinol | HAT inhibitor
From $70.00CAS:78824-30-3Catalog Number:10-1337Activity:HAT inhibitorMolecular Weight:602.8Molecular Formula:C38H50O6Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).Physical Properties:Yellow solidPurity:>95%Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. Garcinol is prone to oxidation. Protect from exposure to air.Shipping Code:RT -
GSK126 | EZH2 methyltransferase inhibitor
From $70.00CAS:1346574-57-9Catalog Number:10-3394Activity:EZH2 methyltransferase inhibitorChemical Names:N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-methyl-1-[(1S)-1-methylpropyl]-6-[6-(1-piperazinyl)-3-pyridinyl]-1H-indole-4-carboxamideMolecular Weight:526.69Molecular Formula:C31H38N6O2Solubility:Soluble in DMSO (16 mg/ml)Physical Properties:Cream solidPurity:>98% HPLC/TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
GSK2879552 | Potent and selective LSD1 inhibitor
From $80.00CAS:1401966-69-5Catalog Number:10-4020Activity:Potent and selective LSD1 inhibitorChemical Name:4-[[4-[[[(1R,2S)-2-Phenylcyclopropyl]amino]methyl]-1-piperidinyl]methyl]benzoic acid dihydrochlorideMolecular Weight:437.40Molecular Formula:C23H28N2O2 • HClSolubility:Soluble in DMSO (up to 25 mg/ml) or in Water (up to at least 25 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT -
GSK3326595 | Selective PRMT5 inhibitor
From $50.00CAS:1616392-22-3Catalog Number:10-4028Activity:Selective PRMT5 inhibitorChemical Name:6-[(1-Acetylpiperidine-4-yl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyrimidine-4-carboxamideAlternate Name:EPZ015938; PemrametostatMolecular Weight:452.56Molecular Formula:C24H32N6O3Solubility:Soluble in DMSO (up to 20 mg/ml).Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT
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