Epigenetics

  • EPZ015666 | Potent and selective PRMT5 inhibitor

    CAS:
    1616391-65-1
    Catalog Number:
    10-4031
    Activity:
    Potent and selective PRMT5 inhibitor
    Chemical Name:
    (S)-N-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide
    Molecular Weight:
    383.44
    Molecular Formula:
    C20H25N5O3
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $90.00
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  • FB23-2 | FTO inhibitor

    CAS:
    2243736-45-8
    Catalog Number:
    10-4852
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  • Garcinol | HAT inhibitor

    CAS:
    78824-30-3
    Catalog Number:
    10-1337
    Activity:
    HAT inhibitor
    Molecular Weight:
    602.8
    Molecular Formula:
    C38H50O6
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    >95%
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. Garcinol is prone to oxidation. Protect from exposure to air.
    Shipping Code:
    RT
    From $70.00
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  • GSK126 | EZH2 methyltransferase inhibitor

    CAS:
    1346574-57-9
    Catalog Number:
    10-3394
    Activity:
    EZH2 methyltransferase inhibitor
    Chemical Names:
    N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-methyl-1-[(1S)-1-methylpropyl]-6-[6-(1-piperazinyl)-3-pyridinyl]-1H-indole-4-carboxamide
    Molecular Weight:
    526.69
    Molecular Formula:
    C31H38N6O2
    Solubility:
    Soluble in DMSO (16 mg/ml)
    Physical Properties:
    Cream solid
    Purity:
    >98% HPLC/TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $70.00
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  • GSK2879552 | Potent and selective LSD1 inhibitor

    CAS:
    1401966-69-5
    Catalog Number:
    10-4020
    Activity:
    Potent and selective LSD1 inhibitor
    Chemical Name:
    4-[[4-[[[(1R,2S)-2-Phenylcyclopropyl]amino]methyl]-1-piperidinyl]methyl]benzoic acid dihydrochloride
    Molecular Weight:
    437.40
    Molecular Formula:
    C23H28N2O2 • HCl
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Water (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $80.00
    View Product This product has multiple variants. The options may be chosen on the product page
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