Epigenetics
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I-BET762 | BET Bromodomain inhibitor / Suppresses Myc transcription
From $80.00CAS:1260907-17-2Catalog Number:10-4122Activity:BET Bromodomain inhibitor / Supresses Myc transcriptionChemical Name:(4S)- 6-(4-Chlorophenyl)-N-ethyl-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetamideAlternate Names:GSK525762Molecular Weight:423.90Molecular Formula:C22H22ClN5O2Solubility:Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to at least 25 mg/ml)Physical Properties:Tan solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
JIB-04 | pan-JUMONJI histone demethylase inhibitor
From $60.00CAS:199596-05-9Catalog Number:10-1618Activity:pan-JUMONJI histone demethylase inhibitorChemical Name:(E)-5-Chloro-2-(2-(phenyl(pyridine-2-yl)methylene)hydrazinyl)pyridineMolecular Weight:308.76Molecular Formula:C17H13ClN4Solubility:Soluble in DMSO (up to 30 mg/ml)Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
JQ1 (+) | BET Bromodomain inhibitor
From $100.00CAS:1268524-70-4Catalog Number:10-1584Activity:BET Bromodomain inhibitorChemical Name:(6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid 1,1-dimethylethyl esterMolecular Weight:456.99Molecular Formula:C23H25ClN4O2SSolubility:Soluble in DMSO (up to 60 mg/ml) or in Ethanol (up to 46 mg/ml).Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.Shipping Code:RT
EXPLORE OTHER Cancer
- ADC warheads
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- Chemotherapeutics
- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Gene Regulation/Transcription
- Growth factors
- Immuno-oncology
- Kinases
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- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Ubiquitin proteasome
- Wnt/ß-Catenin
