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Epigenetics

  • JQ1 | Bromodomain inhibitor

    CAS:
    1268524-69-1
    Catalog Number:
    10-1361
    Activity:
    Bromodomain inhibitor
    Chemical Name:
    (6R,S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid 1,1-dimethylethyl ester
    Molecular Weight:
    457
    Molecular Formula:
    C23H25ClN4O2S
    Solubility:
    Soluble in DMSO (up to 9 mg/ml) or in Ethanol (up to 9 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $65.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • LD2 | PRMT9 inhibitor

    CAS:
    1134334-55-6
    Catalog Number:
    10-4872
    Activity:
    PRMT9 inhibitor
    Chemical Names:
    4-Chloro-8-methoxy-5-methyl-5H-pyrimido[5,4-b]indole
    Molecular Weight:
    247.68
    Molecular Formula:
    C12H10ClN3O
    Solubility:
    Soluble in DMSO (at least 40 mg/ml)
    Physical Properties:
    Pale yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • LMK235 | Selective HDAC4/5 inhibitor

    CAS:
    1418033-25-6
    Catalog Number:
    10-4024
    Activity:
    HDAC4/5 inhibitor
    Chemical Names:
    N-[6-(Hydroxyamino)-6-oxohexoxy]-3,5-dimethylbenzamide
    Molecular Weight:
    294.35
    Molecular Formula:
    C15H22N2O4
    Solubility:
    Soluble in DMSO (25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • MDL-800 | Allosteric activator of SIRT6

    CAS:
    2275619-53-7
    Catalog Number:
    10-4415
    Activity:
    Allosteric activator of SIRT6
    Chemical Names:
    Methyl 2-(N-(5-Bromo-4-fluoro-2-methylphenyl)sulfamoyl)-5-(3,5-dichlorophenylsulfonamido)benzoate
    Molecular Weight:
    626.29
    Molecular Formula:
    C21H16BrCl2FN2O6S2
    Solubility:
    Soluble in DMSO (up to at least 10 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $85.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Mithramycin A | Transcription inhibitor

    CAS:
    18378-89-7
    Catalog Number:
    10-2085
    Activity:
    Transcription inhibitor
    Alternate Names:
    A2371; Antibiotic LA 7017; Aureolic Acid; NSC 24559; PA 144; Plicamycin
    Molecular Weight:
    1085.15
    Molecular Formula:
    C52H76O24
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $42.00
    View Product This product has multiple variants. The options may be chosen on the product page
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