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Immuno-oncology

  • PF-4136309 | CCR2 antagonist

    CAS:
    1341224-83-6
    Catalog Number:
    10-4261
    Activity:
    CCR2 antagonist
    Chemical Name:
    N-[2-[(3S)-3-[[4-Hydroxy-4-(5-pyrimidin-2-ylpyridin-2-yl)cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide
    Alternate Name:
    INCB8761
    Molecular Weight:
    568.60
    Molecular Formula:
    C29H31F3N6O3
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $75.00
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  • Preladenant | Potent and selective adenosine A2A antagonist

    CAS:
    377727-87-2
    Catalog Number:
    10-4102
    Chemical Name:
    4-(Furan-2-yl)-10-[2-[4-[4-(2-methoxyethoxy)phenyl]piperazin-1-yl]ethyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine
    Alternate Name:
    SCH 420814
    Molecular Weight:
    503.57
    Molecular Formula:
    C29H29N9O3
    Solubility:
    Soluble in DMSO (up to 5 mg/ml with warming).
    Physical Properties:
    Beige solid
    Purity:
    >98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $70.00
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    Prochlorperazine maleate | Endocytosis inhibitor

    CAS:
    84-02-6
    Catalog Number:
    10-3474
    Activity:
    Endocytosis inhibitor
    Chemical Name:
    2-Chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine dimaleate
    Molecular Weight:
    606.09
    Molecular Formula:
    C20H24ClN3S • 2C4H4O4
    Solubility:
    Soluble in DMSO (up to 15 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20° (des.)
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $55.00
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  • PSB-KK1445 | GPR18 agonist

    CAS:
    885896-54-8
    Catalog Number:
    10-4918
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  • R428 Chemical structure

    R428 | Potent and selective AXL inhibitor

    CAS:
    1037624-75-1
    Catalog Number:
    10-4676
    Activity:
    Potent and selective AXL inhibitor
    Chemical Name:
    1-(3,4-Diazatricyclo[9.4.0.02,7]pentadeca-1(15),2,4,6,11,13-hexaen-5-yl)-3-N-[(7S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]-1,2,4-triazole-3,5-diamine
    Alternate Names:
    Bemcentinib; BGB324
    Molecular Weight:
    506.64
    Molecular Formula:
    C30H34N8
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
    View Product This product has multiple variants. The options may be chosen on the product page
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