Immuno-oncology Archives | Page 3 of 11

Defactinib | Potent FAK inhibitor

CAS:

1073154-85-4

Catalog Number:

10-4828

Activity:

Potent FAK inhibitor

Chemical Name:

N-Methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]aminl]benzamide

Molecular Weight:

510.50

Molecular Formula:

C₂₀H₂₁F₃N₈O₃S

Solubility:

Soluble in DMSO (up to at least 25mg/ml)

Physical Properties:

White solid

Purity:

98% by HPLC

NMR (Conforms)

Storage Temperature:

-20°C (des.)

Stability:

Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $65.00
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DMXAA | STING agonist

CAS:

117570-53-3

Catalog Number:

10-2676

Activity:

STING agonist

Chemical Name:

5,6-Dimethylxanthenone-4-acetic acid

Alternate Names:

ASA404; Vadimezan

Molecular Weight:

282.29

Molecular Formula:

C₁₇H₁₄O₄

Solubility:

Soluble in DMSO (up to 5 mg/ml) or in DMF (up to 14 mg/ml with warming)

Physical Properties:

Off-white solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

RT

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $60.00
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Dubermatinib | AXL inhibitor

CAS:
1341200-45-0
Catalog Number:
10-4679
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Duvelisib | PI3Kdelta/gamma inhibitor

CAS:

1201438-56-3

Catalog Number:

10-4788

Activity:

PI3Kδ/γ inhibitor/Cancer immunotherapy enhancer

Chemical Name:

8-Chloro-2-phenyl-3-[(1S)-1-(7H-purin-6-ylamino)ethyl]isoquinolin-1-one

Alternative Name:

IPI-145

Molecular Weight:

416.87

Molecular Formula:

C₂₂H₁₇ClN₆O

Solubility:

Soluble in DMSO (up to at least 25 mg/ml)

Physical Properties:

White solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $65.00
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Epacadostat | IDO1 inhibitor

CAS:

1204669-58-8

Catalog Number:

10-4499

Activity:

IDO1 inhibitor/ Cancer immunotherapy enhancer

Chemical Name:

N-(3-Bromo-4-fluorophenyl)-N’-hydroxy-4-{[2-(sulfamoylamino)ethyl]amino}-1,2,5-oxadiazole-3-carboximidamide

Alternate Name:

INCB024360

Molecular Weight:

438.23

Molecular Formula:

C₁₁H₁₃BrFN₇O₄S

Solubility:

Soluble in DMSO (up to at least 25 mg/ml)

Physical Properties:

White solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $45.00
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Immuno-oncology

Defactinib | Potent FAK inhibitor

DMXAA | STING agonist

Dubermatinib | AXL inhibitor

Duvelisib | PI3Kdelta/gamma inhibitor

Epacadostat | IDO1 inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Immuno-oncology

Defactinib | Potent FAK inhibitor

DMXAA | STING agonist

Dubermatinib | AXL inhibitor

Duvelisib | PI3Kdelta/gamma inhibitor

Epacadostat | IDO1 inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21