Immuno-oncology Archives | Page 4 of 11

Everolimus | mTOR inhibitor

CAS:

159351-69-6

Catalog Number:

10-2136

Activity:

mTOR inhibitor

Alternate Names:

SDZ RAD; RAD001

Chemical Name:

40-O-(2-Hydroxyethyl)rapamycin

Molecular Weight:

958.25

Molecular Formula:

C₅₃H₈₄NO₁₄

Solubility:

Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml).

Physical Properties:

White solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.

Shipping Code:

RT

From $55.00
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Galunisertib | Potent TGFB receptor 1 inhibitor / Cancer immunotherapeutic

CAS:

700874-72-2

Catalog Number:

10-4110

Activity:

Potent TGF-β receptor 1 inhibitor / Cancer immunotherapeutic

Chemical Name:

4-[2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide

Alternate Names:

LY2157299

Molecular Weight:

369.43

Molecular Formula:

C₂₂H₁₉N₅O

Solubility:

Soluble in DMSO (up to 25 mg/ml)

Physical Properties:

White solid

Purity:

98%
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Shipping Code:

RT

From $45.00
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Ganetespib | HSP90 inhibitor

CAS:

888216-25-9

Catalog Number:

10-4474

Activity:

HSP90 inhibitor

Chemical Name:

3-(2,4-Dihydroxy-5-propan-2-ylphenyl)-4-(1-methylindol-5-yl)-1H-1,2,4-triazol-5-one;

Molecular Weight:

364.40

Molecular Formula:

C₂₀H₂₀N₄O₃

Solubility:

Soluble in DMSO (up to at least 25 mg/ml)

Physical Properties:

White solid

Purity:

>98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $60.00
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Grapiprant | EP4 Receptor antagonist

CAS:

415903-37-6

Catalog Number:

10-4006

Activity:

EP4 Receptor antagonist

Chemical Name:

1—[2-[4-(2-Ethyl-4,6-dimethylimidazo[4,5-c]pyridine-1-yl)phenyl]ethyl]-3-(4-methylphenyl)sulfonylurea

Alternate Names:

CJ-023423; ARY-007

Molecular Weight:

491.61

Molecular Formula:

C₂₆H₂₉N₅O₃S

Solubility:

Soluble in DMSO (up to at least 10 mg/ml)

Physical Properties:

Off-white solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $80.00
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H-151 | STING Antagonist

CAS:

941987-60-6

Catalog Number:

10-4132

Activity:

STING Antagonist

Chemical Name:

N-(4-Ethylphenyl)-N’-1H-indol-3-yl urea

Molecular Weight:

279.34

Molecular Formula:

C₁₇H₁₇N₃O

Solubility:

Soluble in DMSO (up to 25 mg/ml)

Physical Properties:

Off-white solid

Purity:

98%
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $65.00
Select options

Immuno-oncology

Everolimus | mTOR inhibitor

Galunisertib | Potent TGFB receptor 1 inhibitor / Cancer immunotherapeutic

Ganetespib | HSP90 inhibitor

Grapiprant | EP4 Receptor antagonist

H-151 | STING Antagonist

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Immuno-oncology

Everolimus | mTOR inhibitor

Galunisertib | Potent TGFB receptor 1 inhibitor / Cancer immunotherapeutic

Ganetespib | HSP90 inhibitor

Grapiprant | EP4 Receptor antagonist

H-151 | STING Antagonist

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21