Ubiquitin proteasome
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SKPin C1 | Ubiquitin ligase E3 SCF-Skp2 inhibitor
From $70.00CAS:432001-69-9Catalog Number:10-1441Activity:Ubiquitin ligase E3 SCF-Skp2 inhibitorChemical Names:2-[4-Bromo-2-[[4-oxo-3-(3-pyridinyl¬methyl)-2-thioxo-5-thiazolidinylidene]methyl]-phenoxy]acetic acidMolecular Weight:465.34Molecular Formula:C18H13BrN2O4S2Solubility:Soluble in DMSO (15 mg/ml with warming)Physical Properties:Yellow solidPurity:98% TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 month.Shipping Code:RT -
Spautin-1 | Inhibits autophagy by inhibiting USP 10 and 13
From $65.00CAS:1262888-28-7Catalog Number:10-1367Activity:Inhibits autophagy by inhibiting USP 10 and 13Chemical Name:6-Fluoro-N[(4-fluorophenyl)methyl]-4-quinazolinamineMolecular Weight:271.27Molecular Formula:C15H11F2N3Solubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 15 mg/ml with warming).Physical Properties:Tan solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
Thalidomide | E3 UB ligase inhibitor
From $50.00CAS:50-35-1Catalog Number:10-1115Activity:E3 UB ligase inhibitorChemical Name:N-(2,6-Dioxo-3-piperidinyl)phthalimide, racemicMolecular Weight:258.25Molecular Formula:C13H10N2O4Solubility:Soluble in DMSO (up to 5 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
Thiolutin | Inhibitor of the DUB PSMD14
From $60.00CAS87-11-6Catalog Number:10-2106Activity:Inhibitor of the DUB PSMD14Chemical Names:N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)acetamide;
AcetopyrrothinMolecular Weight:228.29Molecular Formula:C8H8N2O2S2Solubility:Soluble in DMSO (up to 15 mg/ml)Physical Properties:Yellow solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 3 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
EXPLORE OTHER Cancer
- ADC warheads
- Angiogenesis
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- Cancer Cell Metabolism
- Cancer Stem Cells
- Cell Cycle
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- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Immuno-oncology
- Kinases
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Wnt/ß-Catenin
