Inhibitors

  • NGI-1 | Oligosaccharyltransferase (OST) inhibitor

    CAS:
    790702-57-7
    Catalog Number:
    10-4291
    Activity:
    Oligosaccharyltransferase (OST) inhibitor
    Chemical Name:
    5-(Dimethylsulfamoyl)-N-(5-methyl-1,3-thiazol-2-yl)-2-(pyrrolidin-1-yl)benzamide
    Alternate Names:
    ML414
    Molecular Weight:
    394.51
    Molecular Formula:
    C17H22N4O3S2
    Solubility:
    Soluble in DMSO (up to 5 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $55.00
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  • Niclosamide | STAT3 signaling inhibitor

    CAS:
    50-65-7
    Catalog Number:
    10-2474
    Activity:
    STAT3 signaling inhibitor
    Chemical Name:
    5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
    Molecular Weight:
    327.13
    Molecular Formula:
    C13H8Cl2N2O4
    Solubility:
    Soluble in DMSO (up to 3 mg/ml), or in Ethanol (up to 6 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $28.00
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  • Nocodazole | Microtubule inhibitor

    CAS:
    31430-18-9
    Catalog Number:
    10-2387
    Activity:
    Microtubule inhibitor/CRISPR enhancer
    Alternate Names:
    R-17934
    Chemical Name:
    Methyl[5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate
    Molecular Weight:
    301.32
    Molecular Formula:
    C14H11N3O3S
    Solubility:
    Soluble in DMSO (up to 10 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT (des.)
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $50.00
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  • NSC663284 | Cdc25 phosphatase inhibitor

    CAS:
    383907-43-5
    Catalog Number:
    10-1352
    Activity:
    Cdc25 phosphatase inhibitor
    Chemical Name:
    6-Chloro-7-[[2-(4-morpholinyl)ethyl]amino]-5,8-quinolinedione
    Molecular Weight:
    321.77
    Molecular Formula:
    C15H16ClN3O3
    Solubility:
    Soluble in DMSO (up to 15 mg/ml), or in Ethanol (up to 55 mg/ml).
    Physical Properties:
    Red solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $90.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • NVP-BEZ235 | PI3-K and mTOR inhibitor

    CAS:
    915019-65-7
    Catalog Number:
    10-2153
    Activity:
    PI 3-K and mTOR inhibitor
    Chemical Name:
    2-Methyl-2-{4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl]phenyl}propanenitrile
    Molecular Weight:
    469.55
    Molecular Formula:
    C30H23N5O
    Solubility:
    Soluble in DMSO (up to 1 mg/ml with warming) or in DMF (up to 10 mg/ml, dissolves slowly, requires heating to 75¡C).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page
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