Hypoxia

  • BAY 87-2243 | HIF-1 / Mitochondrial complex I inhibitor

    CAS:
    1227158-85-1
    Catalog Number:
    10-4910
    Activity:
    HIF-1 / Mitochondrial complex I inhibitor
    Chemical Name:
    5-[1-[[2-(4-Cyclopropylpiperazin-1-yl)pyridin-4-yl]methyl]-5-methylpyrazol-3-yl]-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole
    Molecular Weight:
    525.54
    Molecular Formula:
    C26H26F3N7O2
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $65.00
  • DMOG | Inhibits prolyl hydroxylase domain-containing proteins

    CAS:
    89464-63-1
    Catalog Number:
    10-2371
    Activity:
    Inhibits prolyl hydroxylase domain-containing proteins
    Alternate Names:
    Dimethyloxalylglycine
    Chemical Name:
    N-(2-Methoxy-2-oxoacetyl)glycine methyl ester
    Molecular Weight:
    175.14
    Molecular Formula:
    C6H9NO5
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Protect from light
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions are not stable. Solutions must be made fresh and used within 1 working day.
    Shipping Code:
    RT
    From $60.00
  • Echinomycin | HIF-1alpha inhibitor

    CAS:
    512-64-1
    Catalog Number:
    10-2424
    Activity:
    HIF1α inhibitor
    Alternate Names:
    Quinomycin A; NSC-13502
    Molecular Weight:
    1101.26
    Molecular Formula:
    C51H64N12O12S2
    Solubility:
    Soluble in DMSO (up to 5 mg/ml)
    Physical Properties:
    White to beige solid
    Purity:
    >97% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months
    Shipping Code:
    RT
    From $90.00
  • HIF-2α-I2 | HIF-2α antagonist

    CAS:
    1422955-31-4
    Catalog Number:
    10-1508
    Activity:
    Hif-2α antagonist
    Chemical Name:
    N-(3-Chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine
    Alternate Names:
    TC-S 7009
    Molecular Weight:
    308.65
    Molecular Formula:
    C12H6ClFN4O3
    Solubility:
    Soluble in DMSO (up to 30 mg/ml) or in DMF (up to 35 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $70.00
  • Hinokitiol | Iron Chelator antioxidant

    CAS:
    499-44-5
    Catalog Number:
    10-2211
    Activity:
    Iron Chelator antioxidant
    Alternate Names:
    β-Thujaplicin
    Chemical Name:
    2-Hydroxy-4-isopropyl-2,4,6-cycloheptatrien-1-one
    Molecular Weight:
    164.2
    Molecular Formula:
    C10H12O2
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    >98%
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 4 months.
    Shipping Code:
    RT
    From $52.00
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