Hypoxia

  • IOX 1 | JMJD demethylase inhibitor

    CAS:
    5852-78-8
    Catalog Number:
    10-1426
    Activity:
    JMJD demethylase inhibitor
    Alternate Names:
    5-Carboxy-8HQ
    Chemical Name:
    8-Hydroxy-5-quinolinecarboxylic acid
    Molecular Weight:
    189.17
    Molecular Formula:
    C10H7NO3
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    RT (des.)
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $72.00
  • ISRIB | Integrated stress response inhibitor

    CAS:
    159403-47-8
    Catalog Number:
    10-1539
    Activity:
    Integrated stress response inhibitor
    Chemical Name:
    N.N’-trans-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)acetamide
    Alternate Names:
    trans-ISRIB
    Molecular Weight:
    451.34
    Molecular Formula:
    C22H24Cl2N2O4
    Solubility:
    Soluble in DMSO (up to 5 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
  • KC7F2 | HIF-1α inhibitor

    CAS:
    927822-86-4
    Catalog Number:
    10-4714
    Activity:
    HIF-1alpha inhibitor
    Chemical Name:
    N,N’-(Dithiodi-2,1-ethanediyl)bis[2,5-dichlorobenzenesulfonamide
    Molecular Weight:
    570.38
    Molecular Formula:
    C16H16Cl4N2O4S4
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $60.00
  • Roxadustat | Proyl hydroxylase domain inhibitor / HIF stabilizer

    CAS:
    808118-40-3
    Catalog Number:
    10-4468
    Activity:
    Proyl hydroxylase domain inhibitor / HIF stabilizer
    Chemical Name:
    2-[(4-Hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetic acid
    Alternate Name:
    FG-4592
    Molecular Weight:
    352.35
    Molecular Formula:
    C19H16N2O5
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml).
    Physical Properties:
    Off-white or white solid
    Purity:
    99% by HPLC
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $30.00
  • YC-1 | Soluble guanylyl cyclase activator

    CAS:
    170632-47-0
    Catalog Number:
    10-1581
    Activity:
    Soluble guanylyl cyclase activator
    Chemical Name:
    3-(5′-Hydroxymethyl-2′-furyl)-1-benzylindazole
    Alternate Name:
    Lificiguat
    Molecular Weight:
    304.34
    Molecular Formula:
    C19H16N2O2
    Solubility:
    Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 15 mg/ml).
    Physical Properties:
    Pink solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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