p53
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Nutlin-3 | p53/mdm2 inhibitor
From $100.00CAS:548472-68-0Catalog Number:10-1350Activity:p53/mdm2 inhibitorChemical Name:(±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-oneMolecular Weight:581.51Molecular Formula:C30H30Cl2N4O4Solubility:Soluble in DMSO (up to 50 mg/ml), or in Ethanol (up to 50 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.Shipping Code:RT -
Pifithrin α | p53 inhibitor
From $50.00CAS:63208-82-2Catalog Number:10-2480Activity:p53 inhibitorAlternate Names:PFT-αChemical Name:1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone á HBrMolecular Weight:367.31Molecular Formula:C16H18N2OS HBrSolubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Pifithrin µ | HSP70 inhibitor
From $45.00CAS:64984-31-2Catalog Number:10-1180Activity:HSP70 inhibitorAlternate Names:PES, NSC-303580Chemical Name:2-PhenylethynesulfonamideMolecular Weight:181.21Molecular Formula:C8H7NO2SSolubility:Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml).Physical Properties:White or off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
PRIMA-1MET | Reactivates mutant p53
From $50.00CAS:5291-32-7Catalog Number:10-4175Activity:Reactivates mutant p53Chemical Name:2-(Hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-oneAlternate Names:APR-246Molecular Weight:199.25Molecular Formula:C10H17NO3Solubility:Soluble in DMSO (up to 20 mg/ml)Physical Properties:White solidPurity:95%
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT
