Ubiquitin Proteasome

  • SMER3 | E3 Ubiquitin ligase inhibitor

    CAS:
    67200-34-4
    Catalog Number:
    10-1356
    Activity:
    E3 Ubiquitin ligase inhibitor
    Chemical Name:
    9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one
    Molecular Weight:
    224.18
    Molecular Formula:
    C11H4N4O2S
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $60.00
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  • Spautin-1 | Inhibits autophagy by inhibiting USP 10 and 13

    CAS:
    1262888-28-7
    Catalog Number:
    10-1367
    Activity:
    Inhibits autophagy by inhibiting USP 10 and 13
    Chemical Name:
    6-Fluoro-N[(4-fluorophenyl)methyl]-4-quinazolinamine
    Molecular Weight:
    271.27
    Molecular Formula:
    C15H11F2N3
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 15 mg/ml with warming).
    Physical Properties:
    Tan solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $65.00
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  • Thalidomide | E3 UB ligase inhibitor

    CAS:
    50-35-1
    Catalog Number:
    10-1115
    Activity:
    E3 UB ligase inhibitor
    Chemical Name:
    N-(2,6-Dioxo-3-piperidinyl)phthalimide, racemic
    Molecular Weight:
    258.25
    Molecular Formula:
    C13H10N2O4
    Solubility:
    Soluble in DMSO (up to 5 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Thiolutin | Inhibitor of the DUB PSMD14

    CAS
    87-11-6
    Catalog Number:
    10-2106
    Activity:
    Inhibitor of the DUB PSMD14
    Chemical Names:
    N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)acetamide;
    Acetopyrrothin
    Molecular Weight:
    228.29
    Molecular Formula:
    C8H8N2O2S2
    Solubility:
    Soluble in DMSO (up to 15 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 3 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • WP1130 | DUB inhibitor

    CAS:
    856243-80-6
    Catalog Number:
    10-1351
    Activity:
    DUB inhibitor
    Alternate Names:
    Degrasyn
    Chemical Name:
    (S,E)-3-(6-Bromopyridin-2-yl)-2-cyano-N-(1-phenylbutyl)acrylamide
    Molecular Weight:
    384.28
    Molecular Formula:
    C19H18BrN3O
    Solubility:
    Soluble in DMSO (up to 45 mg/ml), or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $55.00
    View Product This product has multiple variants. The options may be chosen on the product page
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