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Ubiquitin Proteasome

  • MLN4924 | NEDD8 activating enzyme inhibitor

    CAS:
    905579-51-3
    Catalog Number:
    10-1311
    Activity:
    NEDD8 activating enzyme inhibitor
    Chemical Name:
    ((1S,2S,4R)-4-(4-(((S)-2,3-Dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate; Pevonedistat
    Molecular Weight:
    443.53
    Molecular Formula:
    C21H25N5O4S
    Solubility:
    Soluble in DMSO (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $48.00
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  • NAcM-OPT | NEDD8 ligation inhibitor

    CAS:
    2089293-61-6
    Catalog Number:
    10-1636
    Activity:
    NEDD8 ligation inhibitor
    Chemical Name:
    1-Benzyl-1-(1-butylpiperidin-4-yl)-3-(3,4-dichlorophenyl)urea
    Molecular Weight:
    434.40
    Molecular Formula:
    C23H29Cl2N3O
    Solubility:
    Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC/TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as from date of purchase supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $55.00
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  • NSC697923 | E2 ubiquitin-conjugating enzyme inhibitor

    CAS:
    343351-67-7
    Catalog Number:
    10-1418
    Activity:
    Ubiquitin E2 conjugating enzyme inhibitor
    Chemical Name:
    2-[(Methylphenyl)sulfonyl]-5-nitrofuran
    Molecular Weight:
    267.26
    Molecular Formula:
    C11H9NO5S
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 5 mg/ml with warming)
    Physical Properties:
    Pink solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • ONX-0914 chemical structure

    ONX-0914 | Immunoproteasome inhibitor

    CAS:
    960374-59-8
    Catalog Number:
    10-5885
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  • P22077 chemical structure

    P22077 | Selective USP7 inhibitor

    CAS:
    1247819-59-5
    Catalog Number:
    10-4125
    Activity:
    Selective USP7 inhibitor
    Chemical Name:
    1-(5-((2,4-Difluorophenyl)thio)-4-nitrothiophen-2-yl)ethanone
    Molecular Weight:
    315.32
    Molecular Formula:
    C12H7F2NO3S2
    Solubility:
    Soluble in DMSO (up to 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $70.00
    View Product This product has multiple variants. The options may be chosen on the product page
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