Cytokines

  • GSK-J1 | JMJ H3K27 Demethylase inhibitor (Non-cell permeable)

    CAS:
    1373422-53-7
    Catalog Number:
    10-1393
    Activity:
    JMJ H3K27 Demethylase inhibitor (Non-cell permeable)
    Chemical Name:
    N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine
    Molecular Weight:
    389.46
    Molecular Formula:
    C22H23N5O2
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Pale yellow solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase  as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $75.00
  • GSK-J4 | JMJ H3K27 Demethylase inhibitor (Cell Permeable)

    CAS:
    1373423-53-0
    Catalog Number:
    10-1394
    Activity:
    JMJ H3K27 Demethylase inhibitor (Cell Permeable)
    Chemical Name:
    N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester
    Molecular Weight:
    417.48
    Molecular Formula:
    C24H27N5O2
    Solubility:
    Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 40 mg/ml).
    Physical Properties:
    Yellow waxy solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $50.00
  • GSK583 | RIP2 kinase inhibitor

    CAS:
    1346547-00-9
    Catalog Number:
    10-4761
    Activity:
    RIP2 kinase inhibitor
    Chemical Name:
    6-tert-Butylsulfonyl-N-(5-fluoro-1H-indazol-3-yl)quinoline-4-amine
    Molecular Weight:
    398.45
    Molecular Formula:
    C20H19FN4O2S
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml).
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $40.00
  • IQ-1S | JNK3 inhibitor

    CAS:
    1421610-21-0
    Catalog Number:
    10-1513
    Activity:
    JNK3 inhibitor
    Chemical Name:
    11H-Indeno[1,2-b]quinoxaline-11-one oxime, sodium salt
    Molecular Weight:
    269.23
    Molecular Formula:
    C15H8N3O • Na
    Solubility:
    Soluble in DMSO (up to 15 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $40.00
  • ISO-1 | MIF antagonist

    CAS:
    478336-92-4
    Catalog Number:
    10-1185
    Activity:
    MIF antagonist
    Chemical Name:
    (S,R)-3-(4-Hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid, methyl ester
    Molecular Weight:
    235.24
    Molecular Formula:
    C12H13NO4
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
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