Kinases
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BX795 | Dual TBK1/IKKε inhibitor – enhances lentiviral transduction efficiency
From $65.00CAS:702675-74-9Catalog Number:10-4677Activity:Dual inhibitor of TBK1/IKKεChemical Names:N-[3-[[5-Iodo-4-[3-(thiophene-2-carbonylamino)propylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamideMolecular Weight:591.47Molecular Formula:C23H26IN7O2SSolubility:Soluble in DMSO (>25 mg/ml)Physical Properties:Off-white solidPurity:>97% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Defactinib | Potent FAK inhibitor
From $65.00CAS:1073154-85-4Catalog Number:10-4828Activity:Potent FAK inhibitorChemical Name:N-Methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]aminl]benzamideMolecular Weight:510.50Molecular Formula:C20H21F3N8O3SSolubility:Soluble in DMSO (up to at least 25mg/ml)Physical Properties:White solidPurity:98% by HPLCNMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Deucravacitinib | Allosteric TYK2 inhibitor
From $100.00CAS:1609392-27-9Catalog Number:10-4756Activity:Allosteric TYK2 inhibitorChemical Names:6-(Cyclopropanecarbonylamino)-4-[2-methoxy-3-(1-methyl-1,2,4-triazol-3-yl)anilino]-N-(trideuteriomethyl)pyridazine-3-carboxamideAlternate Name:BMS-986165Molecular Weight:425.47Molecular Formula:C20H19D3N8O3Solubility:Soluble in DMSO (25 mg/ml with warming); ethanol (20 mg/ml)Physical Properties:White to off-white solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Duvelisib | PI3Kdelta/gamma inhibitor
From $65.00CAS:1201438-56-3Catalog Number:10-4788Activity:PI3Kδ/γ inhibitor/Cancer immunotherapy enhancerChemical Name:8-Chloro-2-phenyl-3-[(1S)-1-(7H-purin-6-ylamino)ethyl]isoquinolin-1-oneAlternative Name:IPI-145Molecular Weight:416.87Molecular Formula:C22H17ClN6OSolubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Galunisertib | Potent TGFB receptor 1 inhibitor / Cancer immunotherapeutic
From $45.00CAS:700874-72-2Catalog Number:10-4110Activity:Potent TGF-β receptor 1 inhibitor / Cancer immunotherapeuticChemical Name:4-[2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamideAlternate Names:LY2157299Molecular Weight:369.43Molecular Formula:C22H19N5OSolubility:Soluble in DMSO (up to 25 mg/ml)Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT
