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Kinases

  • P505-15 | Highly selective Syk inhibitor

    CAS:
    1370261-97-4
    Catalog Number:
    10-4650
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  • Parthenolide | NFkB inhibitor

    CAS:
    20554-84-1
    Catalog Number:
    10-2096
    Activity:
    NFκB inhibitor
    Molecular Weight:
    248.32
    Molecular Formula:
    C15H20O3
    Solubility:
    Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    97% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $55.00
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  • Pexidartinib | CSF1R inhibitor

    CAS:
    1029044-16-3
    Catalog Number:
    10-4829
    Activity:
    CSF1R inhibitor/Cancer immunotherapy enhancer
    Chemical Name:
    5-[(5-Chloro-1H-pyrrolo[2,3.b]pyridine-3-yl)methyl]-N-[[6-(trifluoromethyl)pyridin-3-yl]methyl]pyridin-2-amine
    Alternate Names:
    PLX3397
    Molecular Weight:
    417.81
    Molecular Formula:
    C20H15ClF3N5
    Solubility:
    Soluble in DMSO (up to at least 10 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $45.00
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  • PLX5622 | Highly selective CSF1R inhibitor

    CAS:
    1303420-67-8
    Catalog Number:
    10-4726
    Activity:
    Highly selective CSF1R inhibitor
    Chemical Names:
    6-Fluoro-N-[(5-fluoro-2-methoxypyridin-3-yl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridine-3-yl)methyl]pyridine-2-amine
    Molecular Weight:
    395.41
    Molecular Formula:
    C21H19F2N5O
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Pale yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $70.00
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  • R428 Chemical structure

    R428 | Potent and selective AXL inhibitor

    CAS:
    1037624-75-1
    Catalog Number:
    10-4676
    Activity:
    Potent and selective AXL inhibitor
    Chemical Name:
    1-(3,4-Diazatricyclo[9.4.0.02,7]pentadeca-1(15),2,4,6,11,13-hexaen-5-yl)-3-N-[(7S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]-1,2,4-triazole-3,5-diamine
    Alternate Names:
    Bemcentinib; BGB324
    Molecular Weight:
    506.64
    Molecular Formula:
    C30H34N8
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
    View Product This product has multiple variants. The options may be chosen on the product page
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