Kinases
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Pexidartinib | CSF1R inhibitor
From $45.00CAS:1029044-16-3Catalog Number:10-4829Activity:CSF1R inhibitor/Cancer immunotherapy enhancerChemical Name:5-[(5-Chloro-1H-pyrrolo[2,3.b]pyridine-3-yl)methyl]-N-[[6-(trifluoromethyl)pyridin-3-yl]methyl]pyridin-2-amineAlternate Names:PLX3397Molecular Weight:417.81Molecular Formula:C20H15ClF3N5Solubility:Soluble in DMSO (up to at least 10 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
PLX5622 | Highly selective CSF1R inhibitor
From $70.00CAS:1303420-67-8Catalog Number:10-4726Activity:Highly selective CSF1R inhibitorChemical Names:6-Fluoro-N-[(5-fluoro-2-methoxypyridin-3-yl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridine-3-yl)methyl]pyridine-2-amineMolecular Weight:395.41Molecular Formula:C21H19F2N5OSolubility:Soluble in DMSO (>25 mg/ml)Physical Properties:Pale yellow solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
R428 | Potent and selective AXL inhibitor
From $75.00CAS:1037624-75-1Catalog Number:10-4676Activity:Potent and selective AXL inhibitorChemical Name:1-(3,4-Diazatricyclo[9.4.0.02,7]pentadeca-1(15),2,4,6,11,13-hexaen-5-yl)-3-N-[(7S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]-1,2,4-triazole-3,5-diamineAlternate Names:Bemcentinib; BGB324Molecular Weight:506.64Molecular Formula:C30H34N8Solubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
SB 202190 | p38 MAP kinase inhibitor
From $30.00CAS:152121-30-7Catalog Number:10-2172Activity:p38 MAP kinase inhibitorChemical Name:4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenolMolecular Weight:331.35Molecular Formula:C20H14N3OFSolubility:Soluble in DMSO (up to 30 mg/ml).Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.Shipping Code:RT -
SB 203580 | p38 MAP kinase inhibitor
From $60.00CAS:152121-47-6Catalog Number:10-2173Activity:p38 MAP kinase inhibitorChemical Name:4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)imidazoleMolecular Weight:377.44Molecular Formula:C21H16N3OSFSolubility:Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 10 mg/ml with warming).Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT
