Neuroprotection

  • GPI-16552 | PARG inhibitor

    CAS:
    443794-40-9
    Catalog Number:
    10-1502
    Activity:
    PARG inhibitor
    Chemical Name:
    N-bis-(3-Phenyl-propyl)-9-oxo-fluorene-2,7-diamide
    Molecular Weight:
    502.62
    Molecular Formula:
    C33H30N2O3
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in DMF (up to 25 mg/ml).
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • GSK126 | EZH2 methyltransferase inhibitor

    CAS:
    1346574-57-9
    Catalog Number:
    10-3394
    Activity:
    EZH2 methyltransferase inhibitor
    Chemical Names:
    N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-methyl-1-[(1S)-1-methylpropyl]-6-[6-(1-piperazinyl)-3-pyridinyl]-1H-indole-4-carboxamide
    Molecular Weight:
    526.69
    Molecular Formula:
    C31H38N6O2
    Solubility:
    Soluble in DMSO (16 mg/ml)
    Physical Properties:
    Cream solid
    Purity:
    >98% HPLC/TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $70.00
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  • GSK2606414 | PERK inhibitor

    CAS:
    1337531-36-8
    Catalog Number:
    10-4716
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  • GSK2656157 | PERK inhibitor

    CAS:
    1337532-29-2
    Catalog Number:
    10-4855
    Activity:
    PERK inhibitor
    Chemical Names:
    1-[5-(4-Amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-(6-methylpyridin-2-yl)ethanone
    Molecular Weight:
    416.45
    Molecular Formula:
    C23H21FN6O
    Solubility:
    Soluble in DMSO (10 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $40.00
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  • GW-5074 | c-Raf1 inhibitor

    CAS:
    220904-83-6
    Catalog Number:
    10-1031
    Activity:
    c-Raf1 inhibitor
    Chemical Name:
    3-(3,5-Dibromo-4-hydroxybenzylidene)-5-iodo-1,3-dihydroindol-2-one
    Molecular Weight:
    520.95
    Molecular Formula:
    C15H8Br2INO2
    Solubility:
    Soluble in DMSO (up to 50 mg/ml).
    Physical Properties:
    Dark orange solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
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