Fibrosis

  • GW788388 | TGF-ß receptor kinase inhibitor

    CAS:
    452342-67-5
    Catalog Number:
    10-5521
    Activity:
    TGF-ß receptor kinase inhibitor
    Chemical Names:
    4-(4-(3-(Pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide
    Molecular Weight:
    425.49
    Molecular Formula:
    C25H23N5O2
    Solubility:
    Soluble in DMSO (18 mg/ml with warming)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $80.00
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  • IM156 | AMPK activator/Mitochondrial protein complex I inhibitor

    CAS:
    1422365-93-2
    Catalog Number:
    10-4657
    Activity:
    AMPK activator/Mitochondrial complex I inhibitor
    Chemical Names:
    N’-[N’-[4-(Trifluoromethoxy)phenyl]carbamimidoyl]pyrrolidine-1-carboxamidine
    Alternate Name:
    HL156A; Lixumistat
    Molecular Weight:
    315.30
    Molecular Formula:
    C13H16F3N5O
    Solubility:
    Soluble in DMSO (25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Minocycline HCl | Neuroprotective/anti-inflammatory

    CAS:
    13614-98-7
    Catalog Number:
    10-2568
    Activity:
    Neuroprotective; antiapoptotic
    Chemical Name:
    [4S-(4_,4a_,5a_,12a_)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a,tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide hydrochloride
    Molecular Weight:
    493.95
    Molecular Formula:
    C23H27N3O7 HCl
    Solubility:
    Soluble in DMSO (up to 50 mg/ml), or in Water (up to 10 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $60.00
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  • Monocrotaline | Induces pulmonary fibrosis

    CAS:
    315-22-0
    Catalog Number:
    10-2872
    Activity:
    Induces pulmonary fibrosis
    Chemical Name:
    (3R,4R,5R)-4,5,8,10,12,13,13aR,13bR-Octahydro-4,5-dihydroxy-3,4,5-trimethyl-2H-[1,6]dioxacycloundecino[2,3,4-gh]pyrrolizine-2,6(3H)-dione
    Alternate Names:
    Crotaline; MCT; NSC28693
    Molecular Weight:
    325.36
    Molecular Formula:
    C16H23NO6
    Solubility:
    Soluble in DMSO (up to 50 mg/ml with warming), in Ethanol (up to 10 mg/ml with warming) or in organic solvents such as Chloroform (up to 50 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Nintedanib | VEGFR, PDGFR, and FGFR kinase inhibitor

    CAS:
    656247-17-5
    Catalog Number:
    10-3320
    View Product This product has multiple variants. The options may be chosen on the product page
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