Fibrosis
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GW788388 | TGF-ß receptor kinase inhibitor
From $80.00CAS:452342-67-5Catalog Number:10-5521Activity:TGF-ß receptor kinase inhibitorChemical Names:4-(4-(3-(Pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamideMolecular Weight:425.49Molecular Formula:C25H23N5O2Solubility:Soluble in DMSO (18 mg/ml with warming)Physical Properties:Off-white solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
IM156 | AMPK activator/Mitochondrial protein complex I inhibitor
From $60.00CAS:1422365-93-2Catalog Number:10-4657Activity:AMPK activator/Mitochondrial complex I inhibitorChemical Names:N’-[N’-[4-(Trifluoromethoxy)phenyl]carbamimidoyl]pyrrolidine-1-carboxamidineAlternate Name:HL156AMolecular Weight:315.30Molecular Formula:C13H16F3N5OSolubility:Soluble in DMSO (25 mg/ml)Physical Properties:White solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
Minocycline HCl | Neuroprotective/anti-inflammatory
From $60.00CAS:13614-98-7Catalog Number:10-2568Activity:Neuroprotective; antiapoptoticChemical Name:[4S-(4_,4a_,5a_,12a_)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a,tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide hydrochlorideMolecular Weight:493.95Molecular Formula:C23H27N3O7 HClSolubility:Soluble in DMSO (up to 50 mg/ml), or in Water (up to 10 mg/ml).Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.Shipping Code:RT -
Monocrotaline | Induces pulmonary fibrosis
From $50.00CAS:315-22-0Catalog Number:10-2872Activity:Induces pulmonary fibrosisChemical Name:(3R,4R,5R)-4,5,8,10,12,13,13aR,13bR-Octahydro-4,5-dihydroxy-3,4,5-trimethyl-2H-[1,6]dioxacycloundecino[2,3,4-gh]pyrrolizine-2,6(3H)-dioneAlternate Names:Crotaline; MCT; NSC28693Molecular Weight:325.36Molecular Formula:C16H23NO6Solubility:Soluble in DMSO (up to 50 mg/ml with warming), in Ethanol (up to 10 mg/ml with warming) or in organic solvents such as Chloroform (up to 50 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT -
Nintedanib | VEGFR, PDGFR, and FGFR kinase inhibitor
From $45.00Nintedanib (656247-17-5) is a potent inhibitor of VEGFR, PDGFR, FGFR (IC50 = 13-34 nM for VEGFR, 59-65 nM for PDGFR and 37-108 nM for FGFR subtypes).1 Also […]
