PhysioProcesses

Natural products

‘Natural products’ are a fascinating and diverse group of bioactive molecules that are produced by living organisms. These types of compounds are typically divided into two classes: primary metabolites, used for intrinsic function of the producing organism and secondary metabolites, used to increase the competitiveness of the organism within its environment. Both classes of natural products have many potential uses, including drugs (e.g. antibiotics, analgesics, cancer drugs, many others), building blocks for other molecules, and chemical tools/probes (e.g. fluorescence, luminescence).

  • Betulinic Acid | Induces mitochondrial permeability pore opening

    CAS:
    472-15-1
    Catalog Number:
    10-2278
    Activity:
    Induces mitochondrial permeability pore opening
    Chemical Name:
    3ß-Hydroxy-20(29)-lupaene-28-oic acid
    Molecular Weight:
    456.72
    Molecular Formula:
    C30H48O3
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $30.00
  • Blasticidin S HCl | Antibiotic selection agent

    CAS:
    3513-03-9
    Catalog Number:
    10-2830
    Activity:
    Blasticidin S HCl
    Chemical Name:
    (S)-4-[[3-Amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-β-D-erythro-hex-2-enopyranuronic acid hydrochloride
    Molecular Weight:
    458.90
    Molecular Formula:
    C17H26N8O5 &bul; HCl
    Solubility:
    Soluble in Water (greater than 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $80.00
  • Bleomycin sulfate | Induces double strand DNA breaks

    CAS:
    9041-93-4
    Catalog Number:
    10-2623
    Activity:
    Fibrosis-inducing agent
    Source:
    From Streptomyces verticillus
    Molecular Weight:
    1512.62
    Molecular Formula:
    C55H85N17O25S4
    Solubility:
    Soluble in Water (up to 20 mg/ml)
    Physical Properties:
    White or off-white solid
    Purity:
    Contains a mixture of A2 (~70%) and B2 (~30%) forms
    95% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from the date of purchase. Solutions in distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $75.00
  • Bongkrekic Acid | Inhibits MPT pore opening

    CAS:
    11076-19-0
    Catalog Number:
    10-2751
    Activity:
    Inhibits MPT pore opening
    Chemical Name:
    3-Carboxymethyl-17-methoxy-6,18,21-trimethyldocosa-2,4,8,12,18,20-heptaenedioic acid
    Molecular Weight:
    486.61
    Molecular Formula:
    C28H38O7
    Solubility:
    Miscible with DMSO.
    Physical Properties:
    Solution at 1 mg/mL (2 mM) in 0.01M Tris buffer pH 7.5 (contains 1 mg net bongkrekic acid per mL)
    Purity:
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    Blue Ice
    From $160.00
  • Borrelidin | Angiogenesis inhibitor

    CAS:
    7184-60-3
    Catalog Number:
    10-1399
    Activity:
    Angiogenesis inhibitor
    Alternate Names:
    U-78548; C2989; Treponemycin
    Chemical Name:
    Fermentation from Streptomyces sp.
    Molecular Weight:
    489.66
    Molecular Formula:
    C28H43NO6
    Solubility:
    Soluble in DMSO or in Ethanol.
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $190.00
  • Brefeldin A | Inhibits intracellular transport

    CAS:
    20350-15-6
    Catalog Number:
    10-1071
    Activity:
    Inhibits intracellular transport
    Alternate Names:
    Fermentation product from Penicillium brefeldianum
    Molecular Weight:
    280.37
    Molecular Formula:
    C16H24O4
    Solubility:
    Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $38.00
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