PI3K

  • 3-Methyladenine | Autophagosome inhibitor

    CAS:
    5142-23-4
    Catalog Number:
    10-2686
    Activity:
    Autophagosome inhibitor
    Alternate Names:
    3-MA
    Chemical Name:
    3-Methyl-3H-purin-6-amine
    Molecular Weight:
    149.15
    Molecular Formula:
    C6H7N5
    Solubility:
    Soluble in DMSO (up to 3 mg/ml), or in DMF (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $30.00
  • AS-041164 | PI3-Kgamma inhibitor

    CAS:
    6318-41-8
    Catalog Number:
    10-1035
    Activity:
    PI 3-Kγ inhibitor
    Chemical Name:
    5-(1,3-Benzodioxol-5-yl)methylidene-1,3-thiazolidine-2,4-dione
    Molecular Weight:
    249.24
    Molecular Formula:
    C11H7NO4S
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $54.00
  • AS-605240 | PI 3-Kinase inhibitor

    CAS:
    348450-29-7
    Catalog Number:
    10-2575
    Activity:
    PI 3-Kinase inhibitor
    Chemical Name:
    5-(6-Quinoxalinylmethylene)-2,4-thiazolidine-2,4-dione
    Molecular Weight:
    257.27
    Molecular Formula:
    C12H7N2O3
    Solubility:
    Soluble in DMSO (up to 1.5 mg/ml with warming)
    Physical Properties:
    Red solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
  • Buparlisib | PI3-kinase inhibitor

    CAS:
    944396-07-0
    Catalog Number:
    10-4325
    Activity:
    pan-Class I PI3-kinase inhibitor
    Chemical Names:
    5-(2,6-Dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyridine-2-amine; NVP-BKM120
    Molecular Weight:
    410.39
    Molecular Formula:
    C18H21F3N6O2
    Solubility:
    Soluble in DMSO (15 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
  • Duvelisib | PI3Kdelta/gamma inhibitor

    CAS:
    1201438-56-3
    Catalog Number:
    10-4788
    Activity:
    PI3Kδ/γ inhibitor/Cancer immunotherapy enhancer
    Chemical Name:
    8-Chloro-2-phenyl-3-[(1S)-1-(7H-purin-6-ylamino)ethyl]isoquinolin-1-one
    Alternative Name:
    IPI-145
    Molecular Weight:
    416.87
    Molecular Formula:
    C22H17ClN6O
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
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