Bone and Connective Tissue
Diseases of bone (such as osteoporosis) and connective tissue (rheumatoid arthritis, lupus) can be studied in cell and animal models with small molecules that regulate immunity, inflammation, protein folding, and certain key kinases like JAK.
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GW-2580 | cFMS kinase inhibitor
From $72.00CAS:870483-87-7Catalog Number:10-2143Activity:cFMS kinase inhibitorChemical Name:5-(3-Methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamineMolecular Weight:366.32Molecular Formula:C20H22N4O3Solubility:Soluble in DMSO (up to 40 mg/ml).Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
GW-9662 | PPAR gamma antagonist
From $45.00CAS:22978-25-2Catalog Number:10-2622Activity:PPAR gamma antagonistChemical Name:2-Chloro-5-nitrobenzanilideMolecular Weight:276.68Molecular Formula:C13H9ClN2O3Solubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 10 mg/ml).Physical Properties:White or off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
Harmine | MAO-A and DYRK inhibitor
From $25.00CAS:343-27-1Catalog Number:10-4520Activity:MAO-A and DYRK inhibitorChemical Name:7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole hydrochlorideMolecular Weight:248.71Molecular Formula:C13H12N2O HClSolubility:Soluble in Water (up to 25 mg/ml).Physical Properties:White solidPurity:>98% by TLCStorage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.Shipping Code:RT -
Ibandronate | Farnesyl pyrophosphatase synthase inhibitor / osteoporosis drug
From $30.00CAS:138926-19-9Catalog Number:10-4630Activity:Farnesyl pyrophosphatase synthase inhibitor / osteoporosis drugChemical Name:(1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid sodium monohydrateMolecular Weight:359.23Molecular Formula:C9H22NO7P2•Na • H2OSolubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Kartogenin | Induces chrondrocyte differentiation
From $50.00CAS:4727-31-5Catalog Number:10-1372Activity:Induces chrondrocyte differentiationChemical Name:2-[(1,1′-Biphenyl)-4-ylcarbamoyl]benzoic acidMolecular Weight:317.35Molecular Formula:C20H15NO3Solubility:Soluble in DMSO (up to 60 mg/ml) or in Ethanol (up to 14 mg/ml).Physical Properties:White solidPurity:99% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
LDN-193189 | Inhibitor of ALK2 and ALK3
From $60.00CAS:1435934-00-1Catalog Number:10-4764Activity:Inhibitor of ALK2 and ALK3Chemical Name:4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline dihydrochlorideMolecular Weight:479.40Molecular Formula:C25H22N6·2HClSolubility:Soluble in DMSO or in Water (up to 5 mg/ml)Physical Properties:Orange-yellow solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 2 months.Shipping Code:RT
