Bone and Connective Tissue

Diseases of bone (such as osteoporosis) and connective tissue (rheumatoid arthritis, lupus) can be studied in cell and animal models with small molecules that regulate immunity, inflammation, protein folding, and certain key kinases like JAK.

  • Z-Phe-Tyr-CHO | Cathepsin L inhibitor

    CAS:
    167498-29-5
    Catalog Number:
    10-3079
    Activity:
    Cathepsin L inhibitor
    Alternate Names:
    Z-FY-CHO; Z-Phe-Tyr-Aldehyde; SB-412515
    Molecular Weight:
    446.50
    Molecular Formula:
    C26H26N2O5
    Solubility:
    Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 50 mg/ml)
    Physical Properties:
    Off-white to pale yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $30.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Zoledronic acid | Inhibitor of bone resorption

    CAS:
    118072-93-8
    Catalog Number:
    10-4512
    Activity:
    Antiproliferative and apopototic effects
    Alternate Names:
    CGP 42446
    Chemical Name:
    [1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid)
    Molecular Weight:
    272.09
    Molecular Formula:
    C5H10N2O7P2
    Solubility:
    Soluble in Water (up to 2 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by HPLC
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $45.00
    View Product This product has multiple variants. The options may be chosen on the product page
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