Natural products
Showing 1–12 of 172 results
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Ion channels
4,9-Anhydrotetrodotoxin | Selective sodium channel blocker
4,9-Anhydrotetrodotoxin (13072-89-4) is a highly selective blocker of the Na(v1.6) sodium channel. (IC50's: Na(v1.2) = 260 nM, Na(v1.3) = 341 nM, N...$125.00 – $995.00 Select options -
Atherosclerosis
5alpha,6alpha-Epoxycholesterol | LXR ligand
5α,6α-Epoxycholesterol (1250-95-9) is a naturally occurring metabolite of cholesterol. It is a major oxysterol found in processed food1 and has be...$25.00 – $60.00 Select options -
Cancer
Actinomycin D | Transcription inhibitor
Actinomycin D (50-76-0) is a cyclopeptide antibiotic and intercalating transcription inhibitor with anti-neoplastic activity. Potent inhibitor of R...$50.00 – $200.00 Select options -
Ions and other channels
Alamethicin | Pore-forming antimicrobial peptide
Alamethicin (27061-78-5) is a membrane permeabilizing, pore-forming agent.1 Applications include: [32P] incorporation into phosphatidylinositols2, ...$35.00 – $105.00 Select options -
Cancer
Alpha-Mangostin | STING agonist (human)
α-Mangostin (6147-11-1) is a xanthone natural product that has historically been used in traditional folk medicine.1 It is a potent agonist of huma...$50.00 – $190.00 Select options -
Anoikis
Anisomycin | Anoikis sensitizer
Anisomycin (22862-76-6) activates JNK/SAPKs and reduces c-fos and c-jun. Protein synthesis inhibitor. Anisomycin induces apoptosis and sensitizes c...$35.00 – $120.00 Select options -
Apoptosis
Ansamitocin P3 | Microtubule depolymerizer
Ansamitocin P3 (66547-09-9) is a fungal metabolite from Actinosynnema pretiosum which binds to the phomopsin A/rhizoxin site on tubulin.1,2 Ansamit...$50.00 – $120.00 Select options -
Bone and Connective Tissue
Ansatrienin B | Cytotoxic activity
Ansatrienin b (82189-04-6) represents a novel class of ansamycins.1 Inhibits osteoclastic bone resorption.2 Potentiates the activity of several cli...$345.00 Select options -
ATPase
Antibiotic A-23187 | Ca2+ ionophore
Antibiotic A-23187 (52665-69-7) is a highly selective divalent cation ionophore, commonly used to increase intracellular Ca2+ levels in intact cell...$90.00 – $360.00 Select options -
Apoptosis
Aphidicolin | DNA polymerase inhibitor
Aphidicolin (38966-21-1) specifically inhibits DNA polymerase α and δ via binding to the enzyme, in eukaryotic cells such as the HeLa cell line, wi...$70.00 – $280.00 Select options -
Antifungals
Apicidin | HDAC inhibitor
Apicidin (183506-66-3) is a fungal toxin that is a potent, cell permeable inhibitor of histone deacetylases (HDAC's).1 It also displays antitumor p...$55.00 – $220.00 Select options -
Apoptosis
Apoptolidin | Apoptosis inducer
Apoptolidin (194874-06-1) is a powerful inducer of apoptosis in a variety of cancer cell lines.1 Is believed to act via inhibition of F0F1-ATPase2 ...$248.00 Select options
