Natural products

‘Natural products’ are a fascinating and diverse group of bioactive molecules that are produced by living organisms. These types of compounds are typically divided into two classes: primary metabolites, used for intrinsic function of the producing organism and secondary metabolites, used to increase the competitiveness of the organism within its environment. Both classes of natural products have many potential uses, including drugs (e.g. antibiotics, analgesics, cancer drugs, many others), building blocks for other molecules, and chemical tools/probes (e.g. fluorescence, luminescence).

  • Vinblastine sulfate | Microtubule depolymerizer

    CAS:
    143-67-9
    Catalog Number:
    10-2050
    Activity:
    Microtubule depolymerizer
    Alternate Names:
    Vincaleukoblastine
    Molecular Weight:
    909.08
    Molecular Formula:
    C46H58N4O9 H2SO4
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Water (up to 50 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Stability:
    Store for up to 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $48.00
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  • Vincristine sulfate | Microtubule depolymerizer

    CAS:
    2068-78-2
    Catalog Number:
    10-2570
    Activity:
    Microtubule depolymerizer
    Alternate Names:
    Leurocristine sulfate
    Chemical Name:
    22-Oxovincaleukoblastine sulfate
    Molecular Weight:
    923.06
    Molecular Formula:
    C46H56N4O10
    Solubility:
    Soluble in Water (up to 80 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $30.00
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  • Vinpocetine | PDE1 inhibitor

    CAS:
    42971-09-5
    Catalog Number:
    10-1126
    Activity:
    PDE1 inhibitor
    Chemical Name:
    (3α,16α)-Eburnamenine-14-carboxylic acid ethyl ester
    Molecular Weight:
    350.45
    Molecular Formula:
    C22H26N2O2
    Solubility:
    Soluble in DMSO (up to 5 mg/ml), in ethanol (up to 15 mg/ml) or in DMF (up to 3 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO, Ethanol, or DMF may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $30.00
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  • Visnagin| Protects against doxorubicin-induced cardiomyopathy

    CAS:
    82-57-5
    Catalog Number:
    10-4614
    Activity:
    Protects against doxorubicin-induced cardiomyopathy
    Chemical Name:
    4-Methoxy-7-methyl-5H-furo[3,2-g][1]benzopyran-5-one
    Source:
    Isolated from Ammi visnaga
    Molecular Weight:
    230.22
    Molecular Formula:
    C13H10O4
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $35.00
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  • Withaferin A | NFkB and angiogenesis inhibitor

    CAS:
    5119-48-2
    Catalog Number:
    10-2114
    Activity:
    NFκB and angiogenesis inhibitor
    Chemical Name:
    (4β, 5β, 6β, 22R)-5,6-Epoxy-4,22,27-trihydroxy-1-oxoergosta-2,24-dien-26-oic acid δ-lactone
    Molecular Weight:
    470.60
    Molecular Formula:
    C28H38O6
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $65.00
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  • Wortmannin | PI3K inhibitor

    CAS:
    19545-26-7
    Catalog Number:
    10-2115
    Activity:
    PI3K inhibitor
    Chemical Name:
    [(1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-6,11,16-trioxo-13,17-dioxapentacyclo[10.6.1.02,10.05,9.015,19]nonadeca-2(10),12(19),14-trien-3-yl] acetate
    Molecular Weight:
    428.44
    Molecular Formula:
    C23H24O8
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Dried aliquots evaporated from ethanol may be stored at -20° for several months. Solutions however are not stable and must be used within one working day. Note: Wortmannin decomposes fairly quickly in culture media
    Shipping Code:
    RT
    From $42.00
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