Natural products

‘Natural products’ are a fascinating and diverse group of bioactive molecules that are produced by living organisms. These types of compounds are typically divided into two classes: primary metabolites, used for intrinsic function of the producing organism and secondary metabolites, used to increase the competitiveness of the organism within its environment. Both classes of natural products have many potential uses, including drugs (e.g. antibiotics, analgesics, cancer drugs, many others), building blocks for other molecules, and chemical tools/probes (e.g. fluorescence, luminescence).

  • Toyocamycin | Unfolded protein response (UPR) inhibitor

    CAS:
    606-58-6
    Catalog Number:
    10-2750
    Activity:
    Unfolded protein response (UPR) inhibitor
    Chemical Name:
    4-Amino-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
    Alternate Names:
    7-Deaza-7-cyanoadenosine; NSC 63701; NSC 99843; Neuro 000027; Unamycin B; Vengicide
    Molecular Weight:
    291.26
    Molecular Formula:
    C12H13N5O4
    Solubility:
    Soluble in DMSO (up to 25 mg/ml)
    Physical Properties:
    White or off-white solid
    Purity:
    97% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $70.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Triacsin C | Acyl-CoA synthase inhibitor

    CAS:
    76896-80-5
    Catalog Number:
    10-2109
    Activity:
    Acyl-CoA synthase inhibitor
    Chemical Name:
    (3E)-1-Hydroxy-3-((2E,4Z,7E)-undeca-2,4,7-triene-1-ylidene)triaz-1-ene
    Molecular Weight:
    207.28
    Molecular Formula:
    C11H17N3O
    Solubility:
    Supplied in solution in DMSO at a concentration of 1 mg/ml. Maximum solubility in DMSO is 25 mg/ml.
    Physical Properties:
    Solution in DMSO
    Purity:
    95% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions further diluted with DMSO may be stored at -20° for up to 2 months.
    Shipping Code:
    Blue Ice
    From $90.00
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  • Trichostatin A | HDAC inhibitor

    CAS:
    58880-19-6
    Catalog Number:
    10-2110
    Activity:
    HDAC inhibitor
    Alternate Names:
    TSA
    Chemical Name:
    (2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
    Molecular Weight:
    302.38
    Molecular Formula:
    C17H22N2O3
    Solubility:
    Soluble in DMSO (up to 15 mg/ml), or in Ethanol (up to 3 mg/ml).
    Physical Properties:
    Tan solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $78.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Triptolide | Immunosuppressant

    CAS:
    38748-32-2
    Catalog Number:
    10-2631
    Activity:
    Immunsuppressant
    Chemical Name:
    (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-3b,4,4a,6,6a,7a,7b,8b,9,10-Decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one
    Alternate Names:
    PG490
    Molecular Weight:
    360.40
    Molecular Formula:
    C20H24O6
    Solubility:
    Soluble in DMSO (up to 7 mg/ml)
    Physical Properties:
    Tan solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $35.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Tropodithietic acid | Cytotoxic disulfide antibiotic

    CAS:
    750590-18-2
    Catalog Number:
    10-3307
    Activity:
    Cytotoxic disulfide antibiotic
    Chemical Name:
    Oxo-8,9-dithiabicyclo[5.2.0]non-1,4,6-triene-2-carboxylic acid
    Molecular Weight:
    212.25
    Molecular Formula:
    C8H4O3S2
    Solubility:
    Soluble in DMSO (up to 5 mg/ml)
    Physical Properties:
    Orange solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $150.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Tryptanthrin | Immunomodulator/IDO2 inhibitor

    CAS:
    13220-57-0
    Catalog Number:
    10-2228
    Activity:
    Immunomodulator; IDO2 inhibitor
    Chemical Name:
    Indolo(2,1-b)quinazoline-6,12-dione
    Alternate Names:
    NSC 349447; Couroupitine A
    Molecular Weight:
    248.24
    Molecular Formula:
    C15H8N2O2
    Solubility:
    Soluble in DMSO (up to 24 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $55.00
    View Product This product has multiple variants. The options may be chosen on the product page
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Plymouth Meeting, PA USA
1-855-FOCUS21

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