New Products

We will continue to add new products to our already extensive portfolio – check back often for the latest breakthroughs. If you can’t find what you need, contact us for information on custom synthesis.

  • PFI-3 | Selective Bromodomain family VIII inhibitor

    CAS:
    1819363-80-8
    Catalog Number:
    10-4034
    Activity:
    Selective Bromodomain family VIII inhibitor
    Chemical Names:
    (2E)-1-(2-Hydroxyphenyl)-3-[(1R,4R)-5-(pyridine-2-yl)-2,5-diazabicyclo{2.2.1]heptan-2-yl]prop-2-en-1-one
    Molecular Weight:
    321.37
    Molecular Formula:
    C19H19N3O2
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $59.00
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  • JQ1 (+) | BET Bromodomain inhibitor

    CAS:
    1268524-70-4
    Catalog Number:
    10-1584
    Activity:
    BET Bromodomain inhibitor
    Chemical Name:
    (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid 1,1-dimethylethyl ester
    Molecular Weight:
    456.99
    Molecular Formula:
    C23H25ClN4O2S
    Solubility:
    Soluble in DMSO (up to 60 mg/ml) or in Ethanol (up to 46 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $100.00
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  • Ceapin-A7 | ATF6α/UPR inhibitor

    CAS:
    2323027-38-7
    Catalog Number:
    10-3974
    Activity:
    ATF6α/UPR inhibitor
    Chemical Names:
    N-(1-{[2,4-bis(Trifluoromethyl)phenyl]methyl}-1H-pyrazol-4-yl)-5-(furan-2-yl)-1,2-oxazole-3-carboxamide
    Molecular Weight:
    470.33
    Molecular Formula:
    C20H12F6N4O3
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $75.00
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  • Saxagliptin HCl | DPP-IV inhibitor

    CAS:
    709031-78-7
    Catalog Number:
    10-4076
    Activity:
    DPP-IV inhibitor
    Chemical Names:
    (1S,3S,5S)-2-[(2S)-2-Amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride; BMS-477118
    Molecular Weight:
    416.45
    Molecular Formula:
    C18H25N3O2·HCl
    Solubility:
    Soluble in DMSO (20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $39.00
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  • Belnacasan | ICE/caspase-1 inhibitor

    CAS:
    273404-37-8
    Catalog Number:
    10-4399
    Activity:
    ICE/caspase-1 inhibitor
    Chemical Names:
    (S)-1-((S)-2-(4-Amino-3-chlorobenzamido)-3,3-dimethylbutanoyl)-N-((2R,3S)-2-ethoxy-5-oxotetrahydrofuran-3-yl)pyrrolidine-2-carboxamide; VX-765
    Molecular Weight:
    508.99
    Molecular Formula:
    C24H33ClN4O6
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white to white solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $45.00
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  • Enzalutamide | Non-steroidal antiandrogen

    CAS:
    915087-33-1
    Catalog Number:
    10-3910
    Activity:
    Non-steroidal antiandrogen
    Chemical Names:
    4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide; MDV3100
    Molecular Weight:
    464.44
    Molecular Formula:
    C21H16F4N4O2S
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White to off-white solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $40.00
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  • WP631 | SP-1 activated transcription inhibitor

    CAS:

    Not available

    Catalog Number:
    10-3497
    Activity:
    SP-1 activated transcription inhibitor
    Chemical Names:

    4-Methylbenzyl-N-bis[daunomycin], mesylate salt

    Molecular Weight:
    1349.38
    Molecular Formula:
    C62H64N2O20 ∙ 2CH3SO3H
    Solubility:
    Soluble in DMSO (up to 5 mg/ml)
    Physical Properties:
    Red solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des,)
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
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  • CCT251236 | HSF1 inhibitor

    CAS:
    1693731-40-6
    Catalog Number:
    10-4410
    Activity:
    Heat Shock Transcription Factor 1 stress pathway inhibitor
    Chemical Names:
    N-[5-(2,3-Dihydro-1,4-benzodioxine-6-carbonylamino)-2-methylphenyl]-2-(2-pyrrolidin-1-ylethoxy)quinoline-6-carboxamide
    Molecular Weight:
    552.63
    Molecular Formula:
    C32H32N4O5
    Solubility:
    Soluble in DMSO (5 mg/ml)
    Physical Properties:
    Off-white/beige solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $90.00
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  • AZD-2098 | CCR4 antagonist

    CAS:
    566203-88-1
    Catalog Number:
    10-4262
    Activity:
    CCR4 antagonist
    Chemical Names:
    2,3-Dichloro-N-(3-methoxypyrazine-2-yl)benzenesulfonamide
    Molecular Weight:
    334.17
    Molecular Formula:
    C11H9Cl2N3O3S
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white/beige solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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  • PTC-209 | BMI-1 inhibitor

    CAS:
    315704-66-6
    Catalog Number:
    10-4022
    Activity:
    BMI-1 inhibitor
    Chemical Names:
    N-(2,6-Dibromo-4-methoxyphenyl)-4-(2-methylimidazol[1,2-a]pyrimidin-3-yl)-2-thiazolamine
    Molecular Weight:
    495.19
    Molecular Formula:
    C17H13Br2N5OS
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • AA147 | ATF6 activator

    CAS:
    393121-74-9
    Catalog Number:
    10-3973
    Activity:
    Activator of ER stress sensing protein ATF6
    Chemical Names:
    N-(2-Hydroxy-5-methylphenyl)-3-phenylpropanamide; Compound 147
    Molecular Weight:
    255.32
    Molecular Formula:
    C16H17NO2
    Solubility:
    Soluble in DMSO (>25 mg/ml); ethanol (>25 mg/mL)
    Physical Properties:
    Beige to pale orange solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $45.00
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  • Thiolutin | Inhibitor of the DUB PSMD14

    CAS
    87-11-6
    Catalog Number:
    10-2106
    Activity:
    Inhibitor of the DUB PSMD14
    Chemical Names:
    N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)acetamide;
    Acetopyrrothin
    Molecular Weight:
    228.29
    Molecular Formula:
    C8H8N2O2S2
    Solubility:
    Soluble in DMSO (up to 15 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 3 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • MDL-800 | Allosteric activator of SIRT6

    CAS:
    2275619-53-7
    Catalog Number:
    10-4415
    Activity:
    Allosteric activator of SIRT6
    Chemical Names:
    Methyl 2-(N-(5-Bromo-4-fluoro-2-methylphenyl)sulfamoyl)-5-(3,5-dichlorophenylsulfonamido)benzoate
    Molecular Weight:
    626.29
    Molecular Formula:
    C21H16BrCl2FN2O6S2
    Solubility:
    Soluble in DMSO (up to at least 10 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $85.00
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  • 10-XXXX | Wnt/β-catenin (canonical)

    From $5,000.00
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  • Buparlisib | PI3-kinase inhibitor

    CAS:
    944396-07-0
    Catalog Number:
    10-4325
    Activity:
    pan-Class I PI3-kinase inhibitor
    Chemical Names:
    5-(2,6-Dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyridine-2-amine; NVP-BKM120
    Molecular Weight:
    410.39
    Molecular Formula:
    C18H21F3N6O2
    Solubility:
    Soluble in DMSO (15 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • PB28 dihydrochloride | Potent sigma2 agonist

    CAS:
    172907-03-8
    Catalog Number:
    10-4665
    Activity:
    High affinity sigma2 ligand
    Chemical Names:
    1-Cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]piperazine dihydrochloride
    Molecular Weight:
    443.50
    Molecular Formula:
    C24H38N2O
    Solubility:
    Soluble in DMSO (>25 mg/ml) or water (5 mg/ml)
    Physical Properties:
    White to off-white solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $45.00
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  • Autogramin-2 | Autophagy blocker / GRAMD1A inhibitor

    CAS:
    2375541-45-8
    Catalog Number:
    10-4439
    Activity:
    Autophagy blocker / GRAMD1A inhibitor
    Chemical Name:

    t-Butyl 2-[(4-propan-2-yloxybenzoyl)amino]-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-5-carboxylate

    Molecular Weight:
    417.53
    Molecular Formula:
    C21H27N3O4S
    Solubility:
    Soluble in DMSO (up t0 25 mg/ml) or in Ethanol (up to 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $60.00
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  • Ganetespib | HSP90 inhibitor

    CAS:
    888216-25-9
    Catalog Number:
    10-4474
    Activity:
    HSP90 inhibitor
    Chemical Name:

    3-(2,4-Dihydroxy-5-propan-2-ylphenyl)-4-(1-methylindol-5-yl)-1H-1,2,4-triazol-5-one;

    Molecular Weight:
    364.40
    Molecular Formula:
    C20H20N4O3
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • CDN1163 | SERCA activator

    CAS:
    892711-75-0
    Catalog Number:
    10-4627
    Activity:
    Allosteric SERCA activator
    Chemical Names:
    4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide
    Molecular Weight:
    320.39
    Molecular Formula:
    C20H20N2O2
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $55.00
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  • BIIB021 | HSP90 Inhibitor

    CAS:
    848695-25-0
    Catalog Number:
    10-4641
    Activity:
    Potent HSP90 inhibitor
    Chemical Names:
    6-Chloro-9-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]purin-2-amine; CNF2024
    Molecular Weight:
    318.76
    Molecular Formula:
    C14H15ClN6O
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 montha.
    Shipping Code:
    RT
    From $50.00
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