New Products

We will continue to add new products to our already extensive portfolio – check back often for the latest breakthroughs. If you can’t find what you need, contact us for information on custom synthesis.

  • Thiolutin | Inhibitor of the DUB PSMD14

    CAS
    87-11-6
    Catalog Number:
    10-2106
    Activity:
    Inhibitor of the DUB PSMD14
    Chemical Names:
    N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)acetamide;
    Acetopyrrothin
    Molecular Weight:
    228.29
    Molecular Formula:
    C8H8N2O2S2
    Solubility:
    Soluble in DMSO (up to 15 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 3 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • MDL-800 | Allosteric activator of SIRT6

    CAS:
    2275619-53-7
    Catalog Number:
    10-4415
    Activity:
    Allosteric activator of SIRT6
    Chemical Names:
    Methyl 2-(N-(5-Bromo-4-fluoro-2-methylphenyl)sulfamoyl)-5-(3,5-dichlorophenylsulfonamido)benzoate
    Molecular Weight:
    626.29
    Molecular Formula:
    C21H16BrCl2FN2O6S2
    Solubility:
    Soluble in DMSO (up to at least 10 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $85.00
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  • Placeholder

    10-XXXX | Wnt/β-catenin (canonical)

    From $5,000.00
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  • Buparlisib | PI3-kinase inhibitor

    CAS:
    944396-07-0
    Catalog Number:
    10-4325
    Activity:
    pan-Class I PI3-kinase inhibitor
    Chemical Names:
    5-(2,6-Dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyridine-2-amine; NVP-BKM120
    Molecular Weight:
    410.39
    Molecular Formula:
    C18H21F3N6O2
    Solubility:
    Soluble in DMSO (15 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • PB28 dihydrochloride | Potent sigma2 agonist

    CAS:
    172907-03-8
    Catalog Number:
    10-4665
    Activity:
    High affinity sigma2 ligand
    Chemical Names:
    1-Cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]piperazine dihydrochloride
    Molecular Weight:
    443.50
    Molecular Formula:
    C24H38N2O
    Solubility:
    Soluble in DMSO (>25 mg/ml) or water (5 mg/ml)
    Physical Properties:
    White to off-white solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $45.00
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  • Autogramin-2 | Autophagy blocker / GRAMD1A inhibitor

    CAS:
    2375541-45-8
    Catalog Number:
    10-4439
    Activity:
    Autophagy blocker / GRAMD1A inhibitor
    Chemical Name:

    t-Butyl 2-[(4-propan-2-yloxybenzoyl)amino]-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-5-carboxylate

    Molecular Weight:
    417.53
    Molecular Formula:
    C21H27N3O4S
    Solubility:
    Soluble in DMSO (up t0 25 mg/ml) or in Ethanol (up to 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $60.00
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  • Ganetespib | HSP90 inhibitor

    CAS:
    888216-25-9
    Catalog Number:
    10-4474
    Activity:
    HSP90 inhibitor
    Chemical Name:

    3-(2,4-Dihydroxy-5-propan-2-ylphenyl)-4-(1-methylindol-5-yl)-1H-1,2,4-triazol-5-one;

    Molecular Weight:
    364.40
    Molecular Formula:
    C20H20N4O3
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • CDN1163 | SERCA activator

    CAS:
    892711-75-0
    Catalog Number:
    10-4627
    Activity:
    Allosteric SERCA activator
    Chemical Names:
    4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide
    Molecular Weight:
    320.39
    Molecular Formula:
    C20H20N2O2
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $55.00
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  • BIIB021 | HSP90 Inhibitor

    CAS:
    848695-25-0
    Catalog Number:
    10-4641
    Activity:
    Potent HSP90 inhibitor
    Chemical Names:
    6-Chloro-9-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]purin-2-amine; CNF2024
    Molecular Weight:
    318.76
    Molecular Formula:
    C14H15ClN6O
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 montha.
    Shipping Code:
    RT
    From $50.00
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  • Glumetinib | Highly selective c-Met inhibitor

    CAS:
    1642581-63-2
    Catalog Number:
    10-4690
    Activity:
    Highly selective c-Met inhibitor
    Chemical Names:
    6-(1-Methylpyrazol-4-yl)-1-[6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-yl]sulfonylpyrazolo[4,3-b]pyridine: SCC244
    Molecular Weight:
    459.48
    Molecular Formula:
    C21H17N9O2S
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Beige solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $90.00
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  • GSK8612 | Highly selective TBK1 inhibitor

    CAS:
    2361659-62-1
    Catalog Number:
    10-4693
    Activity:
    Highly selective TBK1 inhibitor
    Chemical Names:
    4-[[[5-Bromo-2-[[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]benzenesulfonamide
    Molecular Weight:
    520.33
    Molecular Formula:
    C17H17BrF3N7O2S
    Solubility:
    Soluble in DMSO (20 mg/ml)
    Physical Properties:
    Beige solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $65.00
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  • NVP-231 | Ceramide kinase inhibitor

    CAS:
    362003-83-6
    Catalog Number:
    10-4694
    Activity:
    Reversible ceramide kinase inhibitor
    Chemical Names:
    N-[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3.3.1.13,7]decane-1-carboxamide
    Molecular Weight:
    431.55
    Molecular Formula:
    C25H25N3O3S
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $40.00
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  • PBD-150 | Human glutaminyl cyclase inhibitor

    CAS:
    790663-33-1
    Catalog Number:
    10-4885
    Activity:
    Human glutaminyl cyclase inhibitor
    Chemical Names:
    1-(3,4-Dimethoxyphenyl)-3-93-imidazol-1-ylpropyl)thiourea
    Molecular Weight:
    320.41
    Molecular Formula:
    C15H20N4O2S
    Solubility:
    Soluble in DMSO (25 mg/ml) or ethanol (25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $60.00
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  • TASIN-1 | Induces Apoptosis in cells with APC truncations

    CAS:
    1678515-13-3
    Catalog Number:
    10-4890
    Activity:
    Induces apoptosis in cells with APC truncations
    Chemical Names:
    1-[1-(4-Methoxyphenyl)sulfonylpiperidin-4-yl]-4-methylpiperidine hydrochloride
    Molecular Weight:
    388.95
    Molecular Formula:
    C18H28N2O3S·HCl
    Solubility:
    Soluble in DMSO (20 mg/ml)
    Physical Properties:
    White to off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $70.00
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  • Bepridil | Calcium channel blocker\Active against SARS-CoV2

    CAS:
    74764-40-2
    Catalog Number:
    10-4958
    Activity:
    Calcium channel blocker/anti-SARS-CoV2
    Chemical Name:
    N-Benzyl-N-[3-(2-methylpropoxy)-2-pyrrolidin-1-ylpropyl]aniline hydrochloride
    Molecular Weight:
    403.00
    Molecular Formula:
    C24H34N2O·HCl
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or ethanol (up to 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • GRL-0667 | Noncovalent inhibitor of SARS-CoV PLpro

    CAS:
    1234195-91-5
    Catalog Number:
    10-4963
    Activity:
    Noncovalent SARS-CoV Plpro inhibitor
    Chemical Names:
    1-[(R)-1-(1-Naphthyl)ethyl)]-4-[3,4-(methylenedioxy)benzylamino]carbonylpiperidine
    Molecular Weight:
    416.52
    Molecular Formula:
    C26H28N2O3
    Solubility:
    Soluble in DMSO (>25 mg/ml) or ethanol (15 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $95.00
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  • DAPI | Fluorescent DNA stain

    CAS:
    28718-90-3
    Catalog Number:
    10-5065
    Activity:
    Fluorescent DNA stain
    Chemical Name:

    4′,6-Diamidino-2-phenylindole, dihydrochloride

    Molecular Weight:
    350.25
    Molecular Formula:
    C16H15N5·2HCl
    Solubility:
    Soluble in DMSO (up to 35 mg/ml) or water (up to 20 mg/ml with warming)
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC/HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    PROTECT FROM LIGHT! Stable for 2 years as supplied. Solutions in DMSO may be aliquoted and stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $45.00
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  • Isohelenin | NFkB inhibitor

    CAS:
    470-17-7
    Catalog Number:
    10-5393
    Activity:
    NFkB inhibitor
    Chemical Name:

    (3aR,8aR,9aR)-8a-Methyl-3,5-dimethylenedecahydronaphtho[2,3-b]furan-2(3H)-one

    Molecular Weight:
    232.32
    Molecular Formula:
    C15H20O2
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or ethanol (30 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% TLC

    NMR (Conforms)

    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • CID1067700 | Rab7 GTPase inhibitor

    CAS:
    314042-01-8
    Catalog Number:
    10-5401
    Activity:
    Rab7 GTPase inhibitor
    Chemical Name:

    2-[[(Benzoylamino)thioxomethyl]amino]-4,7-dihydro-5,5-dimethyl-5H-thieno[2,3-c]pyran-3-carboxylic acid; ML282

    Molecular Weight:
    390.48
    Molecular Formula:
    C18H18N2O4S2
    Solubility:
    Soluble in DMSO (up to 40 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $65.00
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  • PI-103 | Potent inhibitor of PI3-kinase, mTOR, and DNA-PK

    CAS:
    371935-74-9
    Catalog Number:
    10-5406
    Activity:
    Potent inhibitor of PI3-kinase, mTOR and DNA-PK
    Chemical Name:

    3-[4-(4-Morpholinyl)pyrido[3’,2’:4,5]furo[3,2-d]pyrimidin-2-yl]-phenol

    Molecular Weight:
    348.36
    Molecular Formula:
    C19H16N4O3
    Solubility:
    Soluble in DMSO (up to 40 mg/ml)
    Physical Properties:
    White solid
    Purity:

    98% by TLC
    NMR (Conforms)

    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

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