Mirabegron | beta-3 Adrenergic agonist
CAS:
223673-61-8
Catalog Number:
10-4228
Obesity and metabolic diseases
Obesity and other metabolic disorders (such as fatty liver disease) are closely linked to diabetes, which in turn is tightly associated with glucose and fatty acid metabolism, circadian clock, mitochondrial function, inflammation, and many others. Focus Biomolecules offers many inhibitors and other modulators of the pathways involved in these processes.
Metabolic syndrome
UNC7467 | IP6K inhibitor
CAS:
2922283-43-8
Catalog Number:
10-4080
SLU-PP-332 | ERR pan-agonist/Exercise mimetic
CAS:
303760-60-3
Catalog Number:
10-3948
NASH/NAFLD
BI01383298 | Citrate transporter inhibitor
CAS:
2227549-00-8
Catalog Number:
10-4191
GSK620 | BD2 selective BET inhibitor
CAS:
2088410-46-0
Catalog Number:
10-4180
DT-109 | Induces glutathione biosynthesis
CAS:
14857-82-0
Catalog Number:
10-5732
Activity:
Induces glutathione biosynthesis
Chemical Names:
Glycyl-glycyl-L-leucine; Gly-Gly-Leu-OH
Molecular Weight:
245.28
Molecular Formula:
C10H19N3O4
Solubility:
Soluble in DMSO (25 mg/ml with warming); Water (25 mg/ml)
Physical Properties:
White solid
Purity:
>98% TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Shipping Code:
RT
Other metabolic diseases
Migalastat HCl | Galactosidase inhibitor/Pharmacological chaperone
CAS:
75172-81-5
Catalog Number:
10-2632
KY-226 | PTP1B inhibitor
CAS:
1621673-53-7
Catalog Number:
10-4004
Activity:
PTP1B Inhibitor
Chemical Name:
4-(Biphenyl-4-ylmethylsulfanylmethyl)-N-(hexane-1-sulfonyl)benzoylamide
Molecular Weight:
481.67
Molecular Formula:
C27H31NO3S2
Solubility:
Soluble in DMSO (>25 mg/ml).
Physical Properties:
Off-white solid
Purity:
>98% by TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT
Miglustat HCl | Alpha-glucosidase inhibitor
CAS:
210110-90-0
Catalog Number:
10-2413
Activity:
Alpha-glucosidase inhibitor
Chemical Name:
N-Butyldeoxynojirimycin HCl
Alternate Names:
NB-DNJ
Molecular Weight:
255.74
Molecular Formula:
C10H21NO4 • HCL
Solubility:
Soluble in DMSO (up to 20 mg/ml) or in Water (up to 20 mg/ml)
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
Shipping Code:
RT
