PhysioProcesses

Antibacterials

Antibacterials (or antibiotics) are natural or synthetic compounds that kill (bactericidal) or block the growth (bacteriostatic) of bacteria. They target fundamental biochemical pathways that bacteria use for production of structural components such as cell wall as well as biosynthesis of macromolecules such as proteins and nucleic acids. Modulation of cell membrane permeability is another common target of many antibacterial agents.

  • PK150 | Sorafenib analog with unique antibacterial properties

    CAS:
    2165324-62-7
    Catalog Number:
    10-3960
    Activity:
    Sorafenib analog with unique antibacterial properties
    Chemical Name:
    1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)urea
    Molecular Weight:
    394.68
    Molecular Formula:
    C15H8ClF5N2O3
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $55.00
  • Puromycin | Translation inhibitor

    CAS:
    58-58-2
    Catalog Number:
    10-2100
    Activity:
    Translation inhibitor
    Chemical Name:
    (S)-3′-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]-amino]-3′-deoxy-N,N-dimethyl-adenosine dihydrochloride
    Molecular Weight:
    544.43
    Molecular Formula:
    C22H29N7O5 2HCl
    Solubility:
    Soluble in DMSO (up to 50 mg/ml), or in Water (up to 50 mg/ml).
    Physical Properties:
    Tan solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $50.00
  • Salinomycin Na | Cancer stem cell inhibitor

    CAS:
    55721-31-8
    Catalog Number:
    10-2654
    Activity:
    Cancer stem cell inhibitor
    Chemical Name:
    from Streptomyces albus
    Molecular Weight:
    772.98
    Molecular Formula:
    C42H69O11 Na
    Solubility:
    Soluble in DMSO.
    Physical Properties:
    White solid
    Purity:
    97% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $40.00
  • Sinefungin | Methyltransferase inhibitor

    CAS:
    58944-73-3
    Catalog Number:
    10-2454
    Activity:
    Methyltransferase inhibitor
    Chemical Name:
    5’-Deoxy-5’-(1,4-diamino-4-carboxybutyl)adenosine
    Alternate Names:
    A-9145; Adenosylornithine; Antibiotic 32232RP
    Molecular Weight:
    381.39
    Molecular Formula:
    C15H23N7O5
    Solubility:
    Soluble in Water (up to 20 mg/ml).
    Physical Properties:
    Tan solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    $130.00
  • Sulfasalazine | Anti-inflammatory / antibiotic

    CAS:
    599-79-1
    Catalog Number:
    10-4566
    Activity:
    Anti-inflammatory / antibiotic
    Chemical Name:
    2-Hydroxy-5-{{4-[(2-pyridinylamino)sulfonyl]phenyl}azo}benzoic acid
    Molecular Weight:
    398.39
    Molecular Formula:
    C18H14N4O5S
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Orange solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $20.00
  • Surfactin | Lipopeptide biosurfactant

    CAS:
    24730-31-2
    Catalog Number:
    10-5131
    Activity:
    Lipopeptide biosurfactant
    Source:
    Cyclic peptide produced by Bacillus substilis
    Molecular Weight:
    1036.36 (based on C15 subunit)
    Molecular Formula:
    C53H93N7O13 (based on C15 subunit)
    Solubility:
    Soluble in DMSO (15 mg/ml)
    Physical Properties:
    White to off-white solid
    Purity:
    >98% TLC; HPLC shows mixture of isomers with C14 and C15 side chains predominating.1
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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