Lipid Biosynthesis Inhibitors

  • Metyrapone | Cytochrome P450 inhibitor

    CAS:
    54-36-4
    Catalog Number:
    10-1159
    Activity:
    Cytochrome P450 inhibitor
    Chemical Name:
    2-Methyl-1,2-dipyridin-3-yl-propan-1-one
    Molecular Weight:
    226.27
    Molecular Formula:
    C14H14N2O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $30.00
  • MF-438 | SCD1 inhibitor

    CAS:
    921605-87-0
    Catalog Number:
    10-4558
    Activity:
    SCD1 inhibitor
    Chemical Name:
    2-Methyl-5-(6-(4-(2-trifluoromethyl)phenoxy)piperidin-3-yl)-1,3,4-thiadiazole
    Molecular Weight:
    421.44
    Molecular Formula:
    C19H18F3N5OS
    Solubility:
    Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 2 mg/ml with warming).
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Confirms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $60.00
  • MK-886 | FLAP inhibitor

    CAS:
    118414-82-7
    Catalog Number:
    10-1040
    Activity:
    FLAP inhibitor
    Alternate Names:
    L-663,536
    Chemical Name:
    3-[1-(4-Chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid
    Molecular Weight:
    472.08
    Molecular Formula:
    C27H34ClNO2S
    Solubility:
    Soluble in DMSO (up to 40 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $70.00
  • Myriocin | Blocks sphingolipid biosynthesis

    CAS:
    35891-70-4
    Catalog Number:
    10-2088
    Activity:
    Blocks sphingolipid biosynthesis
    Alternate Names:
    ISP-1
    Chemical Name:
    (2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid
    Molecular Weight:
    401.54
    Molecular Formula:
    C21H39NO6
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    >98%
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 4 months.
    Shipping Code:
    RT
    From $60.00
  • NDI-091143 | Potent allosteric ATP-citrate lyase inhibitor

    CAS:
    2375840-87-0
    Catalog Number:
    10-4841
    Activity:
    Potent allosteric ACLY inhibitor
    Chemical Names:
    Methyl 3-Chloro-5-[(2,4-difluoro-5-phenylphenyl)sulfamoyl]-4-hydroxybenzoate
    Molecular Weight:
    453.84
    Molecular Formula:
    C20H14ClF2NO5S
    Solubility:
    Soluble in DMSO (>50 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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