Lipid Biosynthesis Inhibitors

  • Myriocin | Blocks sphingolipid biosynthesis

    CAS:
    35891-70-4
    Catalog Number:
    10-2088
    Activity:
    Blocks sphingolipid biosynthesis
    Alternate Names:
    ISP-1
    Chemical Name:
    (2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid
    Molecular Weight:
    401.54
    Molecular Formula:
    C21H39NO6
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    >98%
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 4 months.
    Shipping Code:
    RT
    From $58.00
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  • NDI-091143 | Potent allosteric ATP-citrate lyase inhibitor

    CAS:
    2375840-87-0
    Catalog Number:
    10-4841
    Activity:
    Potent allosteric ACLY inhibitor
    Chemical Names:
    Methyl 3-Chloro-5-[(2,4-difluoro-5-phenylphenyl)sulfamoyl]-4-hydroxybenzoate
    Molecular Weight:
    453.84
    Molecular Formula:
    C20H14ClF2NO5S
    Solubility:
    Soluble in DMSO (>50 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $55.00
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  • Ozagrel HCl | Thromboxane synthase inhibitor

    CAS:
    78712-43-3
    Catalog Number:
    10-2767
    Activity:
    Thromboxane synthase inhibitor
    Alternate Names:
    OKY-046
    Chemical Name:
    (2E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2-propenoic acid hydrochloride
    Molecular Weight:
    264.71
    Molecular Formula:
    C13H12N2O2 HCl
    Solubility:
    Soluble in Water (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $56.00
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  • SC-560 | Selective COX-1 inhibitor

    CAS:
    18817-13-2
    Catalog Number:
    10-2531
    Activity:
    Selective COX-1 inhibitor
    Chemical Name:
    5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole
    Molecular Weight:
    352.74
    Molecular Formula:
    C17H12ClF3N2O
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to 10 mg/ml)
    Physical Properties:
    Brown solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • Simvastatin | HMG-CoA reductase inhibitor

    CAS:
    79902-63-9
    Catalog Number:
    10-1018
    Activity:
    HMG-CoA reductase inhibitor
    Alternate Names:
    Mevinolin
    Chemical Name:
    2,2-Dimethyl-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester butanoic acid
    Molecular Weight:
    418.58
    Molecular Formula:
    C25H38O5
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 35 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $50.00
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