Histone Methylation

  • PF-9366 | Methionine adenosyltransferase 2A inhibitor

    CAS:
    72882-78-1
    Catalog Number:
    10-4635
    Activity:
    Methionine adenosyltransferase 2A inhibitor
    Chemical Name:
    2-(7-Chloro-5-phenyl)-[1,2,4]triazolo[4,3-a]quinoline-1-yl)-N,N,dimethylethanamine
    Molecular Weight:
    350.85
    Molecular Formula:
    C20H19ClN4
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Beige solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $60.00
  • PTC-209 | BMI-1 inhibitor

    CAS:
    315704-66-6
    Catalog Number:
    10-4022
    Activity:
    BMI-1 inhibitor
    Chemical Names:
    N-(2,6-Dibromo-4-methoxyphenyl)-4-(2-methylimidazol[1,2-a]pyrimidin-3-yl)-2-thiazolamine
    Molecular Weight:
    495.19
    Molecular Formula:
    C17H13Br2N5OS
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
  • SGC707 | PRMT3 inhibitor

    CAS:
    1687736-54-4
    Catalog Number:
    10-1610
    Activity:
    PRMT3 inhibitor
    Chemical Name:
    1-Isoquinolin-6-yl-3-(2-oxo-2-pyrrolidin-1-yl-ethyl)-urea
    Molecular Weight:
    298.34
    Molecular Formula:
    C16H18N4O2
    Solubility:
    Soluble in DMSO (up to 35 mg/ml)
    Physical Properties:
    Beige solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
  • Sinefungin | Methyltransferase inhibitor

    CAS:
    58944-73-3
    Catalog Number:
    10-2454
    Activity:
    Methyltransferase inhibitor
    Chemical Name:
    5’-Deoxy-5’-(1,4-diamino-4-carboxybutyl)adenosine
    Alternate Names:
    A-9145; Adenosylornithine; Antibiotic 32232RP
    Molecular Weight:
    381.39
    Molecular Formula:
    C15H23N7O5
    Solubility:
    Soluble in Water (up to 20 mg/ml).
    Physical Properties:
    Tan solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    $130.00
  • Tazemetostat | EZH2 inhibitor

    CAS:
    1403254-99-8
    Catalog Number:
    10-4032
    Activity:
    EZH2 inhibitor
    Chemical Name:
    N-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4’-(morpholinomethyl)-[1,1’-biphenyl]-3-carboxamide
    Alternate Name:
    EPZ-6438
    Molecular Weight:
    572.75
    Molecular Formula:
    C34H44N4O4
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $55.00
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