Extracellular matrix / Cell adhesion

Extracellular matrix (ECM), primarily comprising collagen, provides scaffolding for cells but also contains growth factors, proteins, enzymes, and other macromolecules essential for tissue and organ development and function. Adhesion molecules enable attachment to ECM and basement membranes (BM).

Cell Adhesion

  • C19-9 | non-RGD integrin αvß3 receptor inhibitor
    CAS:
    1477482-47-5
    Catalog Number:
    10-3977
  • C-DIM 8 | Nur77 Antagonist
    CAS:
    151358-47-3
    Catalog Number:
    10-5157
    Activity:
    Nur77 antagonist
    Chemical Names:
    1,1-Bis(3’-indolyl)-1-(p-hydroxyphenyl)methane
    Alternate Name:
    DIM-C-pPhOH
    Molecular Weight:
    338.41
    Molecular Formula:
    C23H18N2O
    Solubility:
    Soluble in DMSO (35 mg/ml); ethanol (35 mg/ml)
    Physical Properties:
    Pink solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
  • KNK437 | HSP70 inhibitor
    CAS:
    218924-25-5
    Catalog Number:
    10-5561
    Activity:
    HSP70 inhibitor
    Chemical Names:
    3-(1,3-Benzodioxol-5-ylmethylene)-2-oxo-1-pyrrolidinecarboxaldehyde
    Molecular Weight:
    245.23
    Molecular Formula:
    C13H11NO4
    Solubility:
    Soluble in DMSO (30 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Thiolutin | Inhibitor of the DUB PSMD14
    CAS
    87-11-6
    Catalog Number:
    10-2106
    Activity:
    Inhibitor of the DUB PSMD14
    Chemical Names:
    N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)acetamide;
    Acetopyrrothin
    Molecular Weight:
    228.29
    Molecular Formula:
    C8H8N2O2S2
    Solubility:
    Soluble in DMSO (up to 15 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 3 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • FAK inhibitor 14 | FAK inhibitor
    CAS:
    4506-66-5
    Catalog Number:
    10-2547
    Activity:
    FAK inhibitor
    Alternate Names:
    Y15
    Chemical Name:
    1,2,4,5-Benzenetetramine tetrahydrochloride
    Molecular Weight:
    284.02
    Molecular Formula:
    C6H10N4 4HCl
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Water (up to 15 mg/ml).
    Physical Properties:
    Grey solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
View All Cell Adhesion Products

FAK

  • FAK inhibitor 14 | FAK inhibitor
    CAS:
    4506-66-5
    Catalog Number:
    10-2547
    Activity:
    FAK inhibitor
    Alternate Names:
    Y15
    Chemical Name:
    1,2,4,5-Benzenetetramine tetrahydrochloride
    Molecular Weight:
    284.02
    Molecular Formula:
    C6H10N4 4HCl
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Water (up to 15 mg/ml).
    Physical Properties:
    Grey solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
  • Defactinib | Potent FAK inhibitor
    CAS:
    1073154-85-4
    Catalog Number:
    10-4828
    Activity:
    Potent FAK inhibitor
    Chemical Name:
    N-Methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]aminl]benzamide
    Molecular Weight:
    510.50
    Molecular Formula:
    C20H21F3N8O3S
    Solubility:
    Soluble in DMSO (up to at least 25mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All FAK Products

Metalloproteases

  • PNF1 | Angiogenesis inducer
    CAS:
    10442-95-2
    Catalog Number:
    10-5556
    Activity:
    Angiogenesis inducer
    Chemical Names:
    2-(2-Oxocyclopentyl)isoindoline-1,3-dione; SC-3-149
    Molecular Weight:
    229.24
    Molecular Formula:
    C13H11NO3
    Solubility:
    Soluble in DMSO (35 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Batimastat | Matrix metalloprotease inhibitor (pan-specific)
    CAS:
    130370-60-4
    Catalog Number:
    10-1589
    Activity:
    Matrix metalloproteinase inhibitor (pan-specific)
    Chemical Name:
    (2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamine)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]butanediamide
    Alternate Names:
    BB-94
    Molecular Weight:
    477.64
    Molecular Formula:
    C23H31N3O4S2
    Solubility:
    Soluble in DMSO (up to 45 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • NSC405020 | MT-MMP inhibitor
    CAS:
    7497-07-6
    Catalog Number:
    10-1462
    Activity:
    MT-MMP inhibitor
    Chemical Name:
    3,4-Dichloro-N-(1-methylbutyl)benzamide
    Molecular Weight:
    260.15
    Molecular Formula:
    C12H15NCl2O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Actinonin | Leucyl aminopeptidase inhibitor
    CAS:
    13434-13-4
    Catalog Number:
    10-2549
    Activity:
    Leucyl aminopeptidase inhibitor
    Chemical Name:
    3-[[1-[-2-Hydroxymethyl)-1-pyrrolidinyl)carbonyl]-2-methylpropyl]carbamoyl]-octanohydroxamic acid
    Molecular Weight:
    385.51
    Molecular Formula:
    C19H36N3O5
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
  • Ilomastat (GM-6001) | MMP inhibitor
    CAS:
    142880-36-2
    Catalog Number:
    10-1339
    Activity:
    MMP inhibitor
    Alternate Names:
    GM-6001
    Chemical Name:
    N-[(2R)-2-(Hydroxamidocarbonylmethyl)-4-methylpentanoyl]-L-tryptophan methylamide
    Molecular Weight:
    388.46
    Molecular Formula:
    C20H28N4O4
    Solubility:
    Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    97% by TLC
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
View All Metalloproteases Products

ROCK

  • Chroman 1 | ROCK II inhibitor / Stem cell cytoprotectant
    CAS:
    1273579-40-0
    Catalog Number:
    10-4912
    Activity:
    ROCK II inhibitor / Stem cell cytoprotectant
    Chemical Names:
    (3S)-N-[2,[2-(Dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)phenyl]-6-methoxy-3,4-dihydro-2H-chromen-3-carboxamide
    Molecular Weight:
    436.51
    Molecular Formula:
    C24H28N4O4
    Solubility:
    Soluble in DMSO (at least 50 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
  • Y-27632 dihydrochloride | ROCK family kinase inhibitor
    CAS:
    129830-38-2
    Catalog Number:
    10-2301
    Activity:
    ROCK family kinase inhibitor
    Chemical Name:
    (R)-(+)-trans-4-(1-Aminoethyl)-N-(-4-pyridyl)cyclohexanecarboxamide dihydrochloride
    Molecular Weight:
    320.26
    Molecular Formula:
    C14H21N3O 2HCl
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Methanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or methanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
  • Fasudil HCl | ROCK inhibitor
    CAS:
    105628-07-7
    Catalog Number:
    10-2137
    Activity:
    ROCK inhibitor
    Alternate Names:
    HA-1077
    Chemical Name:
    1-(5-Isoquinolinesulfonyl)homopiperazine HCl
    Molecular Weight:
    327.84
    Molecular Formula:
    C14H17N3O2S HCl
    Solubility:
    Soluble in DMSO (up to 75 mg/ml) or in Water (up to 100 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
View All ROCK Products

20% OFF

For Postdoc
Customers!

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Menu
Menu
Menu
Menu
VIEW DISTRIBUTORS LIST
Facebook Twitter Linkedin
Menu
Menu

Website Created by Advanta Advertising LLC.