C19-9 | non-RGD integrin αvß3 receptor inhibitor
CAS:
1477482-47-5
Catalog Number:
10-3977
Extracellular matrix / Cell adhesion
Extracellular matrix (ECM), primarily comprising collagen, provides scaffolding for cells but also contains growth factors, proteins, enzymes, and other macromolecules essential for tissue and organ development and function. Adhesion molecules enable attachment to ECM and basement membranes (BM).
Cell adhesion
Chroman 1 | ROCK II inhibitor / Stem cell cytoprotectant
CAS:
1273579-40-0
Catalog Number:
10-4912
Activity:
ROCK II inhibitor / Stem cell cytoprotectant
Chemical Names:
(3S)-N-[2,[2-(Dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)phenyl]-6-methoxy-3,4-dihydro-2H-chromen-3-carboxamide
Molecular Weight:
436.51
Molecular Formula:
C24H28N4O4
Solubility:
Soluble in DMSO (at least 50 mg/ml)
Physical Properties:
White solid
Purity:
99% HPLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT
C-DIM 8 | Nur77 Antagonist
CAS:
151358-47-3
Catalog Number:
10-5157
Activity:
Nur77 antagonist
Chemical Names:
1,1-Bis(3’-indolyl)-1-(p-hydroxyphenyl)methane
Alternate Name:
DIM-C-pPhOH
Molecular Weight:
338.41
Molecular Formula:
C23H18N2O
Solubility:
Soluble in DMSO (35 mg/ml); ethanol (35 mg/ml)
Physical Properties:
Pink solid
Purity:
>98% TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT
FAK
FAK inhibitor 14 | FAK inhibitor
CAS:
4506-66-5
Catalog Number:
10-2547
Activity:
FAK inhibitor
Alternate Names:
Y15
Chemical Name:
1,2,4,5-Benzenetetramine tetrahydrochloride
Molecular Weight:
284.02
Molecular Formula:
C6H10N4 4HCl
Solubility:
Soluble in DMSO (up to 20 mg/ml) or in Water (up to 15 mg/ml).
Physical Properties:
Grey solid
Purity:
98% by TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
Shipping Code:
RT
Defactinib | Potent FAK inhibitor
CAS:
1073154-85-4
Catalog Number:
10-4828
Activity:
Potent FAK inhibitor
Chemical Name:
N-Methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]aminl]benzamide
Molecular Weight:
510.50
Molecular Formula:
C20H21F3N8O3S
Solubility:
Soluble in DMSO (up to at least 25mg/ml)
Physical Properties:
White solid
Purity:
98% by HPLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Metalloproteases
PNF1 | Angiogenesis inducer
CAS:
10442-95-2
Catalog Number:
10-5556
Activity:
Angiogenesis inducer
Chemical Names:
2-(2-Oxocyclopentyl)isoindoline-1,3-dione; SC-3-149
Molecular Weight:
229.24
Molecular Formula:
C13H11NO3
Solubility:
Soluble in DMSO (35 mg/ml)
Physical Properties:
Off-white solid
Purity:
>98% TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Batimastat | Matrix metalloprotease inhibitor (pan-specific)
CAS:
130370-60-4
Catalog Number:
10-1589
Activity:
Matrix metalloproteinase inhibitor (pan-specific)
Chemical Name:
(2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamine)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]butanediamide
Alternate Names:
BB-94
Molecular Weight:
477.64
Molecular Formula:
C23H31N3O4S2
Solubility:
Soluble in DMSO (up to 45 mg/ml)
Physical Properties:
White solid
Purity:
98% by HPLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Shipping Code:
RT
NSC405020 | MT-MMP inhibitor
CAS:
7497-07-6
Catalog Number:
10-1462
Activity:
MT-MMP inhibitor
Chemical Name:
3,4-Dichloro-N-(1-methylbutyl)benzamide
Molecular Weight:
260.15
Molecular Formula:
C12H15NCl2O
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT
ROCK
Chroman 1 | ROCK II inhibitor / Stem cell cytoprotectant
CAS:
1273579-40-0
Catalog Number:
10-4912
Activity:
ROCK II inhibitor / Stem cell cytoprotectant
Chemical Names:
(3S)-N-[2,[2-(Dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)phenyl]-6-methoxy-3,4-dihydro-2H-chromen-3-carboxamide
Molecular Weight:
436.51
Molecular Formula:
C24H28N4O4
Solubility:
Soluble in DMSO (at least 50 mg/ml)
Physical Properties:
White solid
Purity:
99% HPLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT
Y-27632 dihydrochloride | ROCK family kinase inhibitor
CAS:
129830-38-2
Catalog Number:
10-2301
Activity:
ROCK family kinase inhibitor
Chemical Name:
(R)-(+)-trans-4-(1-Aminoethyl)-N-(-4-pyridyl)cyclohexanecarboxamide dihydrochloride
Molecular Weight:
320.26
Molecular Formula:
C14H21N3O 2HCl
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Methanol (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
99% by HPLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or methanol may be stored at -20° for up to 3 months.
Shipping Code:
RT
Fasudil HCl | ROCK inhibitor
CAS:
105628-07-7
Catalog Number:
10-2137
Activity:
ROCK inhibitor
Alternate Names:
HA-1077
Chemical Name:
1-(5-Isoquinolinesulfonyl)homopiperazine HCl
Molecular Weight:
327.84
Molecular Formula:
C14H17N3O2S HCl
Solubility:
Soluble in DMSO (up to 75 mg/ml) or in Water (up to 100 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
Shipping Code:
RT
