DNA Topoisomerase
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Irinotecan HCl | Topoisomerase I inhibitor
From $60.00CAS:136572-09-3Catalog Number:10-2146Activity:Topoisomerase I inhibitorChemical Name:(S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3′,4′:6,7]-indolizino[1,2-b]quinolin-9-yl-[1,4′-bipiperidine]-1′-carboxylate hydrochlorideMolecular Weight:677.2Molecular Formula:C33H38N4O6 HCl 3H2OSolubility:Soluble in DMSO (up to 50 mg/ml), in Water (up to 4 mg/ml) or in Ethanol (up to 4 mg/ml).Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO, ethanol or distilled water may be stored at -20° for up to 3 months.Shipping Code:RT -
SN-38 | DNA topoisomerase I inhibitor
From $75.00CAS:86639-52-3Catalog Number:10-2425Activity:DNA topoisomerase I inhibitorChemical Name:7-Ethyl-10-hydroxycamptothecinMolecular Weight:392.41Molecular Formula:C22H20N2O5Solubility:Soluble in DMSO (up to 40 mg/ml).Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT -
ß-Lapachone | Topoisomerase-1 inhibitor
From $52.00CAS:4707-32-8Catalog Number:10-2386Activity:Topoisomerase I inhibitorChemical Name:3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dioneAlternate Name:NSC-26326Molecular Weight:242.27Molecular Formula:C15H14O3Solubility:Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 15 mg/ml)Physical Properties:Orange solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT
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