Transcription
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BRM014 | BRM/BRG1 ATPase inhibitor
From $150.00SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2), also known as Brahma homologue (BRM), together with its close homologue Brahma-related gene 1 (BRG1), […]
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CBL0137 | Inhibitor of the histone chaperone FACT
From $80.00CBL0137 (1197996-80-7) is an anticancer agent that activates p53 and suppresses NF-kB via trapping of the FACT (facilitates chromatin transcription) complex, an important histone chaperone that mediates nucleosome […]
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HC-258 | Covalent TEAD inhibitor
From $70.00HC-258 is a covalent inhibitor of TEAD (transcriptional enhanced associate domain), an important component of the Hippo pathway. It was able to reduce gene expression levels […]
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IMT1 | Mitochondrial DNA transcription inhibitor/RNA Polymerase inhibitor
From $80.00IMT1 (2304621-31-4) is a specific inhibitor of mitochondrial DNA (mtDNA) transcription. It targets an allosteric binding site on human mitochondrial RNA polymerase leading to impairment of […]
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IMT1B | Mitochondrial DNA transcription inhibitor/RNA Polymerase inhibitor
From $125.00IMT1B (2304621-06-3) is a specific inhibitor of mitochondrial DNA (mtDNA) transcription. It targets an allosteric binding site on human mitochondrial RNA polymerase leading to impairment of […]
