DNA Topoisomerase

  • Camptothecin | Topoisomerase I inhibitor

    CAS:
    7689-03-4
    Catalog Number:
    10-1041
    Activity:
    Topoisomerase I inhibitor
    Chemical Name:
    (S)-4-Ethyl-4-hydroxy-1H-pyrano-[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
    Molecular Weight:
    348.35
    Molecular Formula:
    C20H16N2O4
    Solubility:
    Soluble in DMSO (up to 5 mg/ml).
    Physical Properties:
    Tan solid
    Purity:
    98%
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $40.00
  • Doxorubicin HCl | DNA damaging agent

    CAS:
    25316-40-9
    Catalog Number:
    10-2130
    Activity:
    DNA damaging agent
    Alternate Names:
    Adriamycin; NSC-123127
    Molecular Weight:
    579.99
    Molecular Formula:
    C27H29NO11 HCl
    Solubility:
    Soluble in Water (up to 25 mg/ml).
    Physical Properties:
    Red-orange solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $50.00
  • Etoposide | Topoisomerase II inhibitor

    CAS:
    33419-42-0
    Catalog Number:
    10-1123
    Activity:
    Topoisomerase II inhibitor
    Chemical Name:
    4′-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-ß-D-glucopyranoside
    Molecular Weight:
    588.56
    Molecular Formula:
    C29H32O13
    Solubility:
    Soluble in DMSO (up to 30 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months
    Shipping Code:
    RT
    From $50.00
  • Gemcitabine HCl | DNA polymerase inhibitor

    CAS:
    122111-03-9
    Catalog Number:
    10-2140
    Activity:
    DNA polymerase inhibitor
    Alternate Names:
    dFdC
    Chemical Name:
    2′-Deoxy-2′,2′-difluorocytidine hydrochloride
    Molecular Weight:
    299.66
    Molecular Formula:
    C9H11F2N3O4 HCl
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Water (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98%
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $40.00
  • Irinotecan HCl | Topoisomerase I inhibitor

    CAS:
    136572-09-3
    Catalog Number:
    10-2146
    Activity:
    Topoisomerase I inhibitor
    Chemical Name:
    (S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3′,4′:6,7]-indolizino[1,2-b]quinolin-9-yl-[1,4′-bipiperidine]-1′-carboxylate hydrochloride
    Molecular Weight:
    677.2
    Molecular Formula:
    C33H38N4O6 HCl 3H2O
    Solubility:
    Soluble in DMSO (up to 50 mg/ml), in Water (up to 4 mg/ml) or in Ethanol (up to 4 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO, ethanol or distilled water may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $60.00
1 2