ALK

  • A 83-01 | ALK inhibitor

    CAS:
    909910-43-6
    Catalog Number:
    10-1327
    Activity:
    ALK inhibitor
    Chemical Name:
    3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
    Molecular Weight:
    421.53
    Molecular Formula:
    C25H19N5S
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Light yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $50.00
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  • Alectinib | Potent and selective ALK inhibitor

    CAS:
    1256580-46-7
    Catalog Number:
    10-4793
    Activity:
    Potent and selective ALK inhibitor
    Chemical Name:
    9-Ethyl-6,6-dimethyl-8-(4-morpholin-4-ylpiperidin-1-yl)-11-oxo-5H-benzo[b]carbazole-3-carbonitrile
    Alternate Name:
    CH5424802
    Molecular Weight:
    482.62
    Molecular Formula:
    C30H34N4O2
    Solubility:
    Soluble in DMSO (up to 5 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions are not stable and should be prepared fresh daily.
    Shipping Code:
    RT
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  • Brigatinib | pan-ALK inhibitor

    CAS:
    1197953-54-0
    Catalog Number:
    10-5034
    Activity:
    pan-ALK inhibitor
    Chemical Names:
    5-Chloro-N4-[2-(dimethylphosphinyl)phenyl]-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-2,4- pyrimidinediamine
    Alternate Name:
    AP26113
    Molecular Weight:
    584.02
    Molecular Formula:
    C29H39ClN7O2P
    Solubility:
    Soluble in DMSO (1 mg/ml with warming)
    Physical Properties:
    White to off-white solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • Crizotinib | c-MET and ALK inhibitor

    CAS:
    877399-52-5
    Catalog Number:
    10-2626
    Activity:
    c-MET and ALK inhibitor
    Chemical Name:
    3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine
    Alternate Names:
    PF-02341066, PF-1066
    Molecular Weight:
    450.34
    Molecular Formula:
    C21H22Cl2FN5O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml with warming) or in Ethanol (up to 25 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $80.00
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  • Dorsomorphin | AMPK inhibitor

    CAS:
    866405-64-3
    Catalog Number:
    10-1029
    Activity:
    AMPK inhibitor
    Alternate Names:
    Compound C
    Chemical Name:
    6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine
    Molecular Weight:
    399.49
    Molecular Formula:
    C24H25N5O
    Solubility:
    Soluble in DMSO (up to 3 mg/ml).
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
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