mTOR
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AZD8055 | mTOR kinase inhibitor
From $45.00CAS:1009298-09-2Catalog Number:10-4816Activity:mTOR kinase inhibitorChemical Name:(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanolMolecular Weight:465.54Molecular Formula:C25H31N5O4Solubility:Soluble in DMSO (up to 30 mg/ml)Physical Properties:Yellow solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
INK-128 | TORC1/2 inhibitor
From $50.00CAS:1224844-38-5Catalog Number:10-3362Activity:TORC1/2 inhibitorChemical Name:3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amineAlternate Names:MLN-0128Molecular Weight:309.33Molecular Formula:C15H15N7OSolubility:Soluble in DMSO (up to 25 mg/ml)Physical Properties:Off-white solidPurity:98% by TLC/HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
MHY1485 | mTOR activator
From $50.00CAS:326914-06-1Catalog Number:10-1604Activity:mTOR activatorChemical Name:4,6-Di-4-morpholinyl-N-(4-nitrophenyl)-1,3,5-triazin-2-amineMolecular Weight:387.39Molecular Formula:C17H21N7O4Solubility:Soluble in DMSO (up to 20 mg/ml) or in DMF (up to 10 mg/ml)Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.Shipping Code:RT -
NVP-BEZ235 | PI3-K and mTOR inhibitor
From $40.00CAS:915019-65-7Catalog Number:10-2153Activity:PI 3-K and mTOR inhibitorChemical Name:2-Methyl-2-{4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl]phenyl}propanenitrileMolecular Weight:469.55Molecular Formula:C30H23N5OSolubility:Soluble in DMSO (up to 1 mg/ml with warming) or in DMF (up to 10 mg/ml, dissolves slowly, requires heating to 75¡C).Physical Properties:White or off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 1 month.Shipping Code:RT -
PI-103 | Potent inhibitor of PI3-kinase, mTOR, and DNA-PK
From $60.00CAS:371935-74-9Catalog Number:10-5406Activity:Potent inhibitor of PI3-kinase, mTOR and DNA-PKChemical Name:3-[4-(4-Morpholinyl)pyrido[3’,2’:4,5]furo[3,2-d]pyrimidin-2-yl]-phenol
Molecular Weight:348.36Molecular Formula:C19H16N4O3Solubility:Soluble in DMSO (up to 40 mg/ml)Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT
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