Multikinase

  • Ponatinib | Bcr-Abl and multikinase inhibitor

    CAS:
    943319-70-8
    Catalog Number:
    10-5064
    Activity:
    Bcr-Abl and multikinase inhibitor
    Chemical Name:
    3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-benzamide
    Alternate Name:
    AP-24534
    Molecular Weight:
    532.56
    Molecular Formula:
    C29H27F32N6O
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml with warming).
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date  of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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  • Rebastinib | Bcl-Abl1 inhibitor

    CAS:
    1020172-07-9
    Catalog Number:
    10-4689
    View Product This product has multiple variants. The options may be chosen on the product page
  • Ro 31-6045 | MAP Kinase inhibitor

    CAS:
    113963-68-1
    Catalog Number:
    10-1603
    Activity:
    RKIP/Raf-1 kinase disruptor
    Chemical Names:
    1-Methyl-3,4-bis(indol-3-yl)maleimide
    Molecular Weight:
    341.36
    Molecular Formula:
    C21H15N3O2
    Solubility:
    Soluble in DMSO (35 mg/ml); ethanol (9 mg/ml)
    Physical Properties:
    Orange solid
    Purity:
    98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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  • Sitravatinib | Multikinase inhibitor / Immuno-oncology agent

    CAS:
    1123837-84-2
    Catalog Number:
    10-4826
    Activity:
    Multikinase inhibitor / Immuno-oncology agent
    Chemical Name:
    1-N’-[3-Fluoro-4-[2-[5-[(2-methoxyethylamino)methyl]pyridin-2-yl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
    Alternate Names:
    MGCD516
    Molecular Weight:
    629.68
    Molecular Formula:
    C33H29N5O4S
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml), or in Ethanol (up to at least 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Sorafenib | Multi-kinase inhibitor

    CAS:
    284461-73-0
    Catalog Number:
    10-2174
    Activity:
    Inhibitor of Raf-1 and other kinases
    Alternate Names:
    BAY 43-9006
    Chemical Name:
    4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide
    Molecular Weight:
    464.83
    Molecular Formula:
    C21H16ClF3N4O3
    Solubility:
    Soluble in DMSO (up to 200 mg/ml) or in Ethanol (up to 3 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page
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